HINTEGRA 全踝关节置换术：684 例患者的生存率分析。

HINTEGRA total ankle replacement: survivorship analysis in 684 patients.

机构信息

Orthopaedic Department, University Hospital of Basel, University of Basel, Spitalstrasse 21, CH-4031 Basel, Switzerland.

出版信息

J Bone Joint Surg Am. 2013 Jul 3;95(13):1175-83. doi: 10.2106/JBJS.L.01234.

DOI:10.2106/JBJS.L.01234

PMID:23824385

Abstract

BACKGROUND

Total ankle replacement is increasingly recommended for patients with end-stage ankle osteoarthritis. We analyzed the survivorship of 722 arthroplasties performed with one type of three-component total ankle prosthesis.

METHODS

Seven hundred and seventy-nine primary total ankle arthroplasties (741 patients) were performed between May 2000 and July 2010 with use of the HINTEGRA three-component prosthesis. A logistic multiple regression model was used to identify independent risk factors for prosthesis failure in 684 patients (722 ankles). The mean time to final follow-up (and standard deviation) was 6.3 ± 2.9 years.

RESULTS

Seven hundred and twenty-two ankles (684 patients) were available for survivorship analysis at the latest follow-up. The overall survival rates were 94% and 84% after five and ten years, respectively. Sixty-one ankles had a revision arthroplasty (twenty-seven both components, thirteen the tibial component only, and fourteen the talar component only) or were converted to a fusion (seven ankles).There were no polyethylene failures. There were no amputations. The generation category of the prosthesis, the cause of ankle osteoarthritis, and the age of the patient were identified as independent risk factors for prosthesis failure.

CONCLUSIONS

The midterm survivorship of the HINTEGRA implant was comparable with that of other third-generation total ankle replacements.

摘要

背景

全踝关节置换术越来越多地被推荐用于终末期踝关节骨关节炎患者。我们分析了一种三组件全踝关节假体的 722 例关节置换术的存活率。

方法

2000 年 5 月至 2010 年 7 月期间，使用 HINTEGRA 三组件假体对 741 例患者的 779 例初次全踝关节置换术进行了治疗。使用逻辑多元回归模型，对 684 例患者（722 个踝关节）中假体失败的独立危险因素进行了分析。最终随访的平均时间（及标准差）为 6.3±2.9 年。

结果

在最近一次随访中，722 个踝关节（684 例患者）可用于生存分析。5 年和 10 年后的总体生存率分别为 94%和 84%。61 个踝关节行翻修关节成形术（27 个为双组件，13 个为胫骨组件，14 个为距骨组件）或转换为融合术（7 个踝关节）。没有聚乙烯失败。没有截肢。假体的生产代别、踝关节骨关节炎的病因和患者年龄被确定为假体失败的独立危险因素。