Kvarda Peter, Mills Andreea, Shepherd David, Schneider Tim
Melbourne Orthopaedic Group, 33 The Avenue, Windsor, Melbourne, VIC 3181, Australia.
Royal Australasian College of Surgeons, Victoria State Office, 250-290 Spring Street, Melbourne, VIC 3002, Australia.
J Clin Med. 2024 Jan 30;13(3):786. doi: 10.3390/jcm13030786.
Aseptic loosening is one of the most common modes of failure of total ankle replacement (TAR). However, a precise definition of aseptic loosening is still lacking. This systematic review aimed to identify the variations of applied definitions and offer insights into the lack of consensus. Human studies reporting aseptic loosening of TAR published in peer-reviewed journals within the last decade were considered. The search strategy involved specific terms in Embase, MEDLINE ALL, and the Cochrane Library. Variations in aseptic loosening definitions were analysed. Of 767 studies, 88 were included in this study. Only nine studies precisely defined aseptic loosening with significant variations. Twenty-two studies referenced the term and fifty-seven reported it as a complication but neither defined nor referenced it. Significant uncertainty exists regarding the universal definition of aseptic loosening of TAR, and many variations occur in terms of the assessment approach and criteria.
无菌性松动是全踝关节置换术（TAR）最常见的失败模式之一。然而，目前仍缺乏对无菌性松动的精确界定。本系统评价旨在明确所应用定义的差异，并深入探讨缺乏共识的原因。纳入过去十年在同行评审期刊上发表的关于TAR无菌性松动的人体研究。检索策略涉及Embase、MEDLINE ALL和Cochrane图书馆中的特定术语。分析了无菌性松动定义的差异。在767项研究中，本研究纳入了88项。只有9项研究对无菌性松动进行了精确定义，且存在显著差异。22项研究提及了该术语，57项研究将其报告为一种并发症，但均未对其进行定义或引用。关于TAR无菌性松动的通用定义存在重大不确定性，在评估方法和标准方面存在许多差异。
