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荩草中痕量金属的积累及其生物可给性。

Trace metals accumulation in Bacopa monnieri and their bioaccessibility.

机构信息

Laboratory of Analytical Chemistry and Applied Ecochemistry, Faculty of Bioscience Engineering, Ghent University, Gent, Belgium.

出版信息

Planta Med. 2013 Aug;79(12):1081-3. doi: 10.1055/s-0032-1328713. Epub 2013 Jul 3.

DOI:10.1055/s-0032-1328713
PMID:23824547
Abstract

Bacopa monnieri is commonly known as "Brahmi" or "Water hyssop" and is a source of nootropic drugs. Aboveground parts of plant samples collected from peri-urban Indian areas were analysed for total trace metal concentrations. Subsequently, three samples with high concentrations of Cd and Pb were subjected to in vitro gastrointestinal digestion to assess the bioaccessibility of the trace metals in these plants. The total concentrations of trace metals on a dry weight basis were 1.3 to 6.7 mg·kg⁻¹ Cd, 1.5 to 22 mg·kg⁻¹ Pb, 36 to 237 mg·kg⁻¹ Cu, and 78 to 186 mg·kg⁻¹ Zn. The majority of Bacopa monnieri samples exceeded threshold limits of Cd, Pb, Cu, and Zn for use as raw medicinal plant material or direct consumption. Therefore, it is necessary to evaluate Bacopa monnieri collected in nature for their trace metal content prior to human consumption and preparation of herbal formulations.

摘要

印度菹草俗称“ Brahmi”或“水薄荷”,是益智药的来源。对从城市周边地区采集的植物样本的地上部分进行了总痕量金属浓度分析。随后,对三种 Cd 和 Pb 浓度较高的样本进行了体外胃肠消化,以评估这些植物中痕量金属的生物可给性。干重基础上痕量金属的总浓度为 1.3 至 6.7 mg·kg⁻¹ Cd、1.5 至 22 mg·kg⁻¹ Pb、36 至 237 mg·kg⁻¹ Cu 和 78 至 186 mg·kg⁻¹ Zn。大多数印度菹草样本超过了 Cd、Pb、Cu 和 Zn 作为原料药或直接食用的阈值限制。因此,在人类食用和草药制剂制备之前,有必要对自然界中采集的印度菹草进行痕量金属含量评估。

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