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甲状腺手术后的发病率:患者视角。

Morbidity after thyroid surgery: patient perspective.

机构信息

Department of Surgery, John Radcliffe Hospital, Oxford, United Kingdom.

出版信息

Laryngoscope. 2013 Sep;123(9):2319-23. doi: 10.1002/lary.23850. Epub 2013 Jul 3.

Abstract

OBJECTIVES/HYPOTHESIS: To evaluate patient perception of morbidity after thyroid surgery.

STUDY DESIGN

Survey of consecutive patients (case series).

METHODS

A standardized questionnaire was mailed to 312 patients who underwent thyroid surgery during a 3-year period (January 2008 to December 2010).

RESULTS

Replies were received from 202 (64%) patients (56 male, 166 female; age, 55 ± 16 years) at 6 to 39 months (median, 23 months) after lobectomy (n = 119) or total thyroidectomy (n = 76) for benign (n = 160) or malignant (n = 42) conditions. Subjective voice assessment using a visual analogue scale was normal in 111 patients, deteriorated in 80 patients, and improved in 21 patients. Voice handicap index scores were normal in 126 (62%) patients and increased in 76 (38%) patients to a median of 17 (range, 11-29). Voice-related quality of life was excellent in 107 (53%) patients, fair to good in 66 patients, and poor to fair in 29 patients. Subjective assessment of swallowing was reported as normal in 84 patients, moderately affected in 56 patients (score, 11-15) and severely affected in 62 patients (score, 16-40; median, 23). Calcium supplements prescribed routinely after bilateral surgery were interrupted within 2 to 4 weeks in 56 patients and within 3 to 6 months in 18 patients. None of the respondents had persistent hypoparathyroidism. Appearance of the scar assessed using the Manchester score ranged from 5 to 16 (median, 7). Asked whether they would consider robotic thyroid surgery to avoid a cervical scar, only 38 patients said they were definitely interested.

CONCLUSIONS

A large proportion of patients report persistent moderate voice and swallowing problems after thyroid surgery. These findings are similar to a recent international multicenter survey of more than 2,000 patients with thyroid cancer. Hypocalcemia and cosmetic outcome raised no significant concerns.

摘要

目的/假设:评估甲状腺手术后患者的发病情况。

研究设计

连续患者的调查(病例系列)。

方法

在 3 年期间(2008 年 1 月至 2010 年 12 月),对 312 例接受甲状腺手术的患者进行了标准化问卷调查。

结果

术后 6 至 39 个月(中位数 23 个月),202 例(64%)患者(56 例男性,166 例女性;年龄 55 ± 16 岁)回复了调查问卷,他们接受了甲状腺叶切除术(n = 119)或全甲状腺切除术(n = 76),治疗良性(n = 160)或恶性(n = 42)疾病。111 例患者的主观嗓音评估采用视觉模拟量表正常,80 例患者恶化,21 例患者改善。126 例(62%)患者的嗓音障碍指数评分正常,76 例(38%)患者增加至中位数 17(范围 11-29)。107 例(53%)患者的嗓音相关生活质量极好,66 例患者良好至尚可,29 例患者较差至尚可。84 例患者报告吞咽功能正常,56 例患者(评分 11-15)中度影响,62 例患者(评分 16-40;中位数 23)严重影响。双侧手术后常规开具的钙补充剂在 56 例患者中中断 2 至 4 周,在 18 例患者中中断 3 至 6 个月。没有患者出现持续性甲状旁腺功能减退症。采用曼彻斯特评分评估的疤痕外观范围为 5 至 16(中位数 7)。询问患者是否会考虑机器人甲状腺手术以避免颈部疤痕,只有 38 例患者表示肯定有兴趣。

结论

甲状腺手术后,相当大比例的患者报告持续存在中度嗓音和吞咽问题。这些发现与最近一项针对 2000 多例甲状腺癌患者的国际多中心调查相似。低钙血症和美容效果没有引起明显关注。

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