葡聚糖硫酸钠诱导的小鼠炎症性结肠炎模型。
Dextran sodium sulfate-induced murine inflammatory colitis model.
作者信息
Schneider Monika
机构信息
Infectious and Inflammatory Disease Center, Sanford Burnham Medical Research Institute, La Jolla, CA, USA.
出版信息
Methods Mol Biol. 2013;1031:189-95. doi: 10.1007/978-1-62703-481-4_21.
PMID:23824901
Abstract
Colitis is a chronic inflammatory disease of the colon that is characterized by recurring, acute episodes. Mouse models of colitis allow for the study of multiple aspects of this disease, including the innate immune response, epithelial and intestinal cell response, and wound healing. The following protocols cover acute, chronic, and cancer-associated colitis models.
摘要
结肠炎是一种结肠的慢性炎症性疾病，其特征为反复发作的急性发作。结肠炎小鼠模型有助于研究该疾病的多个方面，包括固有免疫反应、上皮和肠道细胞反应以及伤口愈合。以下方案涵盖急性、慢性和癌症相关的结肠炎模型。
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