白三烯 D4 和乙酰甲胆碱反应性预测孟鲁司特治疗哮喘的疗效。
Responsiveness to leukotriene D4 and methacholine for predicting efficacy of montelukast in asthma.
机构信息
State Key Laboratory of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China;
出版信息
J Thorac Dis. 2013 Jun;5(3):298-301. doi: 10.3978/j.issn.2072-1439.2013.02.01.
Abstract
A lower responsiveness to leukotriene D4 (LTD4) or higher LTD4/[methacholine (MCh)] potency ratio might suggest preferable outcomes of short-term montelukast monotherapy in terms of airway inflammation and lung function in asthmatic patients.
摘要
在哮喘患者中，对白细胞三烯 D4（LTD4）的反应性降低或 LTD4/[乙酰甲胆碱（MCh）]效价比升高，可能提示短期单独使用孟鲁司特治疗在气道炎症和肺功能方面具有更好的效果。
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