Patriarca G, di Rienzo V, Schiavino D, Nucera E, Romano A, Pellegrino S, Milani A, Fais G
Servizio di Allergologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Allergol Immunopathol (Madr). 1990 Jan-Feb;18(1):1-4.
Forty-five subjects with rhinitis of suspected allergic origin underwent immune and allergy testing including skin-tests and immuno-enzymatic assay of serum and nasal secretion specific IgE (RAST). Nasal secretion was collected using a cotton tampon inserted in both middle meati. A statistical analysis comparing the results of skin-tests and serum RAST was performed: the results obtained with these two techniques were very homogeneous (86.7% accuracy). An overall concordance (82.2%) was also observed by comparing skin-tests and nasal secretion RAST. Finally, the results of serum and nasal secretion RAST were compared: in this case totally superimposed data were reported (overall accuracy: 93.3%). In all cases the comparison between RAST classes in serum and nasal secretion was carried out: the difference between the semiquantitative evaluation of reaginic concentration classes using these two methods is not statistically significant (chi-square test). This technique of nasal secretion collection is simple and with no risk involved.
45名疑似过敏性鼻炎患者接受了免疫和过敏检测，包括皮肤试验以及血清和鼻分泌物特异性IgE的免疫酶测定（放射变应原吸附试验）。使用插入双侧中鼻道的棉塞收集鼻分泌物。对皮肤试验和血清放射变应原吸附试验的结果进行了统计分析：这两种技术得到的结果非常一致（准确率86.7%）。通过比较皮肤试验和鼻分泌物放射变应原吸附试验，也观察到总体一致性（82.2%）。最后，比较了血清和鼻分泌物放射变应原吸附试验的结果：在这种情况下，报告的数据完全重叠（总体准确率：93.3%）。在所有病例中，均对血清和鼻分泌物中放射变应原吸附试验类别进行了比较：使用这两种方法对反应素浓度类别的半定量评估之间的差异无统计学意义（卡方检验）。这种鼻分泌物收集技术简单且无风险。
