[Determination of the diagnostic efficacy of the multi-RAST test (Phadiotop) in allergic rhinitis].

Diagnosis of IgE mediated allergic rhinitis is based on medical history. Prick-test (of the skin) and determination of increased IgE levels by serum (PRIST and RAST) as well as intranasal provocation test. To search the potential diagnostic value of a multi-RAST test (Phadiotop) in serum and nasal fluids, 508 with rhinitis were studied: In 267 patients nasal allergy was confirmed by the above mentioned tests. Phadiotop revealed a sensitivity of 98.1% in serum and 79.0% in nasal fluid. Specificity of Phadiotop was 95.9% in serum and 97.5% in nasal fluid. Our results show that the determination of Phadiotop can be considered as a very sensitive screening test for allergy detection.