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肥胖患者:麻醉后护理单元中的呼吸并发症

Obese patients: respiratory complications in the post-anesthesia care unit.

作者信息

Mendonça J, Pereira H, Xará D, Santos A, Abelha F J

机构信息

Serviço de Anestesiologia, Centro Hospitalar de São João, Porto, Portugal.

Serviço de Anestesiologia, Centro Hospitalar de São João, Porto, Portugal; Unidade de Anestesiologia e Cuidados Peri-operatórios, Departamento de Cirurgia da Faculdade de Medicina, Universidade do Porto, Porto, Portugal.

出版信息

Rev Port Pneumol. 2014 Jan-Feb;20(1):12-9. doi: 10.1016/j.rppneu.2013.04.002. Epub 2013 Jul 2.

Abstract

INTRODUCTION

Obesity has been associated with respiratory complications, and the majority of these complications occur in the Post-Anesthesia Care Unit (PACU). The aim of this study was to evaluate the outcome and incidence of adverse respiratory events (AREs) in obese patients during their stay in the PACU METHODS: We conducted a prospective control study that included 27 obese patients matched with an equal number of patients with body mass index (BMI)<30 (non-obese control group); the 2 groups of patients were similar in respect to gender distribution, age, and type of surgery and had been admitted into the PACU after elective surgery (May 2011). The AREs were identified during PACU stay. Descriptive analysis of variables was performed, and the Mann-Whitney U test, Chi-square test, or Fisher's exact test were used for comparisons. Associations with AREs were studied using univariate and multivariate logistic regression models.

RESULTS

There was a higher frequency of STOP-BANG ≥3 (89% vs. 11%, P<.001) among obese patients and they were less frequently scheduled to undergo high-risk surgery (7% vs. 41%, P=.005) and major surgery (4% vs. 15%, P=.008). Obese patients had more frequent AREs in the PACU (33% vs. 7%, P<.018). Multivariate analysis identified obesity and residual neuromuscular blockade as independent risk factors for the occurrence of AREs. Stay in the PACU was longer for obese patients (120min vs. 84min, P<.01).

CONCLUSIONS

Obesity was considered an independent risk factor for AREs in the PACU. Obese patients stayed longer in the PACU, but they did not stay longer in the hospital.

摘要

引言

肥胖与呼吸系统并发症相关,且这些并发症大多发生在麻醉后护理单元(PACU)。本研究旨在评估肥胖患者在PACU期间不良呼吸事件(AREs)的结局和发生率。方法:我们进行了一项前瞻性对照研究,纳入了27例肥胖患者,并与同等数量的体重指数(BMI)<30的患者(非肥胖对照组)进行匹配;两组患者在性别分布、年龄和手术类型方面相似,均在择期手术后(2011年5月)进入PACU。在PACU停留期间识别AREs。对变量进行描述性分析,并使用Mann-Whitney U检验、卡方检验或Fisher精确检验进行比较。使用单变量和多变量逻辑回归模型研究与AREs的关联。结果:肥胖患者中STOP-BANG≥3的频率更高(89%对11%,P<.001),且他们较少被安排进行高风险手术(7%对41%,P=.005)和大手术(4%对15%,P=.008)。肥胖患者在PACU中发生AREs的频率更高(33%对7%,P<.018)。多变量分析确定肥胖和残余神经肌肉阻滞是AREs发生的独立危险因素。肥胖患者在PACU的停留时间更长(120分钟对84分钟,P<.01)。结论:肥胖被认为是PACU中AREs的独立危险因素。肥胖患者在PACU停留时间更长,但他们在医院的停留时间并不长。

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