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[患有神经系统疾病男性的性取向]

[Sexuality of men with neurologic disorders].

作者信息

Denys P, Soler J-M, Giuliano F

机构信息

Service de médecine physique et réadaptation, université de Versailles Saint-Quentin-en-Yvelines, hôpital Raymond-Poincaré, AP-HP, 104, boulevard R.-Poincaré, 92380 Garches, France.

出版信息

Prog Urol. 2013 Jul;23(9):712-7. doi: 10.1016/j.purol.2013.01.009. Epub 2013 Feb 28.

Abstract

INTRODUCTION

Neurological disorders affecting the brain, the spinal cord or the peripheral nervous system are frequently responsible for sexual disorders. Their impact can be major and could rank first in the concerns of patients with neurological handicap, particularly those who are paraplegic.

METHODS

Medical literature was reviewed and combined with expert opinion of the authors.

RESULTS

Sexual dysfunction can vary depending on the site of the lesion, its complete or incompleteness for the spinal cord, its natural history, the age of onset. Value of the data present in the literature varies depending on the pathology. Many neurological patients are on medication and an iatrogenic factor is not to be excluded when managing and understanding the physiopathology of sexual dysfunction. Clinical trials evaluating the efficacy of pharmacological treatments are often specific to one pathology. This means that extrapolating to other neurological disorders is difficult and could even be dangerous in the presence of orthostatic hypotension. Due to the vicinity of the spinal centers controlling bladder, sphincteric, anorectal and sexual functions the symptomatology is often mixed associating urinary, sexual and fecal disorders. The treatment of urinary incontinence and management of anorectal disorders should precede the treatment for sexual complaints. The existence of a sexual disorder can be of great help in the neurological diagnosis in certain contexts (extrapyramidal syndromes). We report the data from the literature concerning male sexual disorders in cases of acquired brain lesions (stroke, cranial trauma), extrapyramidal symptoms, medullar lesions, multiple sclerosis, peripheral lesions of the cauda equina or more distal.

CONCLUSION

Sexual dysfunction must be part of the overall management of neurological patients.

摘要

引言

影响大脑、脊髓或周围神经系统的神经疾病常导致性功能障碍。其影响可能很大,在神经功能障碍患者的担忧中可能排在首位,尤其是截瘫患者。

方法

回顾医学文献并结合作者的专家意见。

结果

性功能障碍会因病变部位、脊髓损伤的完全或不完全程度、其自然病史、发病年龄而有所不同。文献中现有数据的价值因病理情况而异。许多神经疾病患者正在服药,在管理和理解性功能障碍的病理生理学时,不能排除医源性因素。评估药物治疗疗效的临床试验通常针对一种病理情况。这意味着将其外推至其他神经疾病很困难,在存在体位性低血压的情况下甚至可能危险。由于控制膀胱、括约肌、肛门直肠和性功能的脊髓中枢相邻,症状往往混合出现,伴有泌尿、性和排便障碍。尿失禁的治疗和肛门直肠疾病的管理应先于性问题的治疗。在某些情况下(锥体外系综合征),性功能障碍的存在对神经诊断有很大帮助。我们报告了文献中有关后天性脑损伤(中风、颅脑外伤)、锥体外系症状、脊髓损伤、多发性硬化症、马尾神经或更远端周围神经损伤病例中男性性功能障碍的数据。

结论

性功能障碍必须成为神经疾病患者整体管理的一部分。

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