Martínez M E, Cárcamo Valor P, Gastón de Iriarte E, Mateos F, Martínez-Piñeiro J A
Servicios de Bioquímica y Urología delHospital La Paz, Facultad de Medicina, Universidad Autónoma, Madrid, España.
Arch Esp Urol. 1990 May;43(4):364-8.
A study to determine the incidence of idiopathic hypercalciuria was performed in 110 patients (59 females, 51 males). Classification of this metabolic disorder according to its different types revealed the following incidence: 50% for absorptive hypercalciuria, 14.5% for hypercalciuria from loss of renal phosphates, and 30% for renal hypercalciuria. Insufficient biochemical data with a significant value did not permit classification of 6.3%. Analysis of distribution according to sex revealed a similar incidence (50%) for males and females for absorptive hypercalciuria, a prevalence in men (71%) for hypercalciuria due to loss of renal phosphates, and a prevalence in females (64.7%) for renal hypercalciuria. However, correction of these data according to the male to female ratio of our study population revealed renal hypercalciuria to be more prevalent in females whereas absorptive hypercalciuria and hypercalciuria from loss of renal phosphates were more prevalent in men. Analysis of distribution according to age revealed a direct relationship between the increased incidence of renal hypercalciuria and patient age.
对110例患者(59例女性,51例男性)进行了一项确定特发性高钙尿症发病率的研究。根据这种代谢紊乱的不同类型进行分类,结果显示其发病率如下:吸收性高钙尿症为50%,肾磷酸盐丢失导致的高钙尿症为14.5%,肾性高钙尿症为30%。因生化数据不足且无显著意义,无法对6.3%的患者进行分类。按性别分析分布情况发现,吸收性高钙尿症在男性和女性中的发病率相似(50%),肾磷酸盐丢失导致的高钙尿症在男性中的患病率为71%,肾性高钙尿症在女性中的患病率为64.7%。然而,根据我们研究人群的男女比例对这些数据进行校正后发现,肾性高钙尿症在女性中更为普遍,而吸收性高钙尿症和肾磷酸盐丢失导致的高钙尿症在男性中更为普遍。按年龄分析分布情况发现,肾性高钙尿症发病率的增加与患者年龄之间存在直接关系。