Intensive Care Unit, Mount Sinai Hospital, University of Toronto, 600 University Avenue, Room 18-214, Toronto, Ontario M5G 1X5, Canada.
Crit Care Clin. 2013 Jul;29(3):509-20. doi: 10.1016/j.ccc.2013.03.006. Epub 2013 Apr 30.
Sepsis accounts for approximately 10% of all maternal deaths. Pregnant women are susceptible to certain infections because of alterations in their cell-mediated immunity. Obstetric sepsis requires early broad-spectrum antibiotic therapy and may necessitate surgical intervention. Group A streptococcal infection may produce necrotizing fasciitis and toxic shock. Pyelonephritis remains a common cause of sepsis during pregnancy, and associated acute respiratory distress syndrome occurs more commonly than in the nonpregnant population. Severe pneumonitis caused by influenza virus and varicella zoster infection may occur. Malaria may be more severe in the pregnant woman, and carries significant risk to both mother and fetus.
败血症约占所有孕产妇死亡的 10%。由于细胞介导免疫的改变，孕妇易发生某些感染。产科败血症需要早期广谱抗生素治疗，可能需要手术干预。A 组链球菌感染可导致坏死性筋膜炎和中毒性休克。肾盂肾炎仍然是妊娠期间败血症的常见原因，与非妊娠人群相比，相关的急性呼吸窘迫综合征更为常见。流感病毒和水痘带状疱疹病毒感染可引起严重肺炎。孕妇的疟疾可能更为严重，对母亲和胎儿都有重大风险。
