Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.
FEBS Lett. 2013 Aug 19;587(16):2584-90. doi: 10.1016/j.febslet.2013.06.038. Epub 2013 Jul 3.
AtATL78 is an Arabidopsis RING E3 ubiquitin ligase. RT-PCR and promoter-GUS assays revealed that AtATL78 was up-regulated by cold stress and down-regulated by drought. AtATL78 was localized at the plasma-membrane. Suppression of AtATL78 increased tolerance to cold stress but decreased tolerance to drought. Our data suggests that AtATL78 is a negative regulator of cold stress response and a positive regulator of drought stress response in Arabidopsis. These results further suggest that AtATL78 plays opposing roles in cold and drought stress responses.
AtATL78 是拟南芥的一个 RING E3 泛素连接酶。RT-PCR 和启动子-GUS 分析显示，AtATL78 受冷胁迫诱导而上调，受干旱胁迫而下调。AtATL78 定位于质膜上。AtATL78 的抑制增强了对冷胁迫的耐受性，但降低了对干旱胁迫的耐受性。我们的数据表明，AtATL78 是拟南芥冷胁迫反应的负调控因子和干旱胁迫反应的正调控因子。这些结果进一步表明，AtATL78 在冷胁迫和干旱胁迫反应中发挥相反的作用。
