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预测髋部骨折后的结局:使用衰弱指数整合全面老年评估结果。

Predicting outcome after hip fracture: using a frailty index to integrate comprehensive geriatric assessment results.

机构信息

Orthogeriatric Team, Cardiff Trauma Unit, University Hospital of Wales, Cardiff, UK.

出版信息

Age Ageing. 2014 Jan;43(1):122-6. doi: 10.1093/ageing/aft084. Epub 2013 Jul 5.

Abstract

INTRODUCTION

hip fracture is expensive in terms of mortality, hospital length of stay (LOS) and consequences for independence. Poor outcome reflects the vulnerability of patients who typically sustain this injury, but the impact of different comorbidities and impairments is complex to understand. We consider this in a prospective cohort study designed to examine how a patients' frailty index (FI) predicts outcome.

METHODOLOGY

consecutive patients with low trauma hip fracture were assessed, excluding only those unfit for surgery. Comprehensive Geriatric Assessment (CGA) findings were used to derive a FI for each patient, which was examined alongside other assessment and outcome data from our National Hip Fracture Database (NHFD) submission for these individuals.

RESULTS

we describe 178 patients; mean age 81 years, 73.5% female. The mean FI was 0.34 (SD = 0.16), and logistic regression identified abbreviated mental test score and FI as the strongest predictors of poor outcome. When patients were stratified by FI, 56 (31.5%) were in the low-frailty group (FI ≤0.25), 58 (32.5%) in intermediate (FI >0.25-0.4), and 64 (36%) in the high-FI group (FI >0.4). All the patients in the low-FI group returned to their original residence within a mean of 21.6 days. The mean LOS for the intermediate group was 36.3 days compared with 67.8 days in the high-FI group (P < 0.01) while 30-day mortality was 3.4% for the intermediate group compared with 17.2% for the high-FI group (P < 0.001).

CONCLUSIONS

individual CGA findings proved disappointing as outcome predictors, while FI turned out to be a better predictor of mortality, 30-day residence and length of inpatient stay.

摘要

简介

髋部骨折在死亡率、住院时间(LOS)和对独立性的影响方面代价高昂。不良预后反映了通常遭受这种伤害的患者的脆弱性,但不同合并症和损伤的影响很难理解。我们在一项前瞻性队列研究中考虑了这一点,旨在研究患者的脆弱性指数(FI)如何预测结果。

方法

对低创伤性髋部骨折的连续患者进行评估,仅排除不适合手术的患者。对每位患者进行综合老年评估(CGA),并使用 CGA 结果得出 FI,同时检查我们国家髋部骨折数据库(NHFD)提交的这些个体的其他评估和结果数据。

结果

我们描述了 178 名患者;平均年龄 81 岁,73.5%为女性。平均 FI 为 0.34(SD=0.16),逻辑回归确定简短精神状态测试评分和 FI 是不良预后的最强预测因素。当根据 FI 对患者进行分层时,56 名患者(31.5%)处于低脆弱性组(FI≤0.25),58 名患者(32.5%)处于中等脆弱性组(FI>0.25-0.4),64 名患者(36%)处于高 FI 组(FI>0.4)。低 FI 组的所有患者平均在 21.6 天内返回原籍住所。中间组的平均 LOS 为 36.3 天,而高 FI 组为 67.8 天(P<0.01),而中间组的 30 天死亡率为 3.4%,而高 FI 组为 17.2%(P<0.001)。

结论

个体 CGA 发现作为结果预测因素令人失望,而 FI 是死亡率、30 天居住地和住院时间的更好预测因素。

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