• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Biochemical and genetic studies on rabbit hemoglobin. II. Electrophoretic polymorphism of the alpha-chain.

作者信息

Ferrand N

机构信息

Instituto de Zoologia, Faculdade de Ciências, Universidade do Porto, Portugal.

出版信息

Biochem Genet. 1990 Apr;28(3-4):117-22. doi: 10.1007/BF00561331.

DOI:10.1007/BF00561331
PMID:2383241
Abstract

A genetic polymorphism of rabbit (Oryctolagus cuniculus) hemoglobin alpha chain is demonstrated by means of acid starch gel electrophoresis. The polymorphism is not detected by isoelectric focusing and may be based upon neutral for neutral amino acid substitutions in accordance with previous findings by means of amino acid sequencing. Segregation analysis was performed on 15 matings with 49 offspring and confirmed the initial genetic hypothesis of three common codominant alleles at an autosomal locus. The calculated gene frequencies in a random sample of 86 unrelated individuals are HBA1 = 0.73, HBA2 = 0.22, and HBA*3 = 0.05.

摘要

相似文献

1
Biochemical and genetic studies on rabbit hemoglobin. II. Electrophoretic polymorphism of the alpha-chain.
Biochem Genet. 1990 Apr;28(3-4):117-22. doi: 10.1007/BF00561331.
2
Biochemical and genetic studies on rabbit hemoglobin. I. Electrophoretic polymorphism of the beta chain.
Biochem Genet. 1989 Dec;27(11-12):673-8. doi: 10.1007/BF02396059.
3
Genetic polymorphism of delta-aminolaevulinic acid dehydratase (E.C. 4.2.1.24, ALAD) in the domestic rabbit.
Anim Genet. 1990;21(2):217-9. doi: 10.1111/j.1365-2052.1990.tb03229.x.
4
Copy number polymorphism in the α-globin gene cluster of European rabbit (Oryctolagus cuniculus).欧洲兔（Oryctolagus cuniculus）α-珠蛋白基因簇的拷贝数多态性。
Heredity (Edinb). 2012 May;108(5):531-6. doi: 10.1038/hdy.2011.118. Epub 2011 Dec 7.
5
Genetic polymorphism of sorbitol dehydrogenase in the brown hare and the distribution of the variation in central Europe.棕兔中山梨醇脱氢酶的遗传多态性及该变异在中欧的分布
Biochem Genet. 1991 Feb;29(1-2):49-54. doi: 10.1007/BF00578239.
6
Genetic polymorphism of transferrin (TF) and the haemoglobin alpha chain (HBA) in the brown hare (Lepus europaeus).欧洲野兔（Lepus europaeus）中转铁蛋白（TF）和血红蛋白α链（HBA）的基因多态性。
Anim Genet. 1993 Dec;24(6):439-40. doi: 10.1111/j.1365-2052.1993.tb00359.x.
7
Evidence for contrasting modes of selection at interacting globin genes in the European rabbit (Oryctolagus cuniculus).欧洲野兔（穴兔）中相互作用的珠蛋白基因的对比选择模式的证据。
Heredity (Edinb). 2008 Jun;100(6):602-9. doi: 10.1038/hdy.2008.26. Epub 2008 Apr 30.
8
Genetic analysis and mapping of biochemical markers in an F2 intercross of two inbred strains of the rabbit (Oryctolagus cuniculus).家兔（穴兔）两个近交系F2代杂交中的生化标记遗传分析与定位
Biochem Genet. 2001 Jun;39(5-6):169-78. doi: 10.1023/a:1010241308643.
9
Evidence for transferrin polymorphism in Spanish wild rabbits.西班牙野兔中转铁蛋白多态性的证据。
Anim Genet. 1987;18(2):125-32. doi: 10.1111/j.1365-2052.1987.tb00751.x.
10
Genetic polymorphism of rabbit (Oryctolagus cuniculus) tissue acid phosphatases (ACP2 and ACP3).
Comp Biochem Physiol B Biochem Mol Biol. 1998 Jun;120(2):405-9. doi: 10.1016/s0305-0491(98)10047-0.

引用本文的文献

1
Evidence for contrasting modes of selection at interacting globin genes in the European rabbit (Oryctolagus cuniculus).欧洲野兔（穴兔）中相互作用的珠蛋白基因的对比选择模式的证据。
Heredity (Edinb). 2008 Jun;100(6):602-9. doi: 10.1038/hdy.2008.26. Epub 2008 Apr 30.
2
The molecular basis of high-altitude adaptation in deer mice.鹿鼠高原适应的分子基础。
PLoS Genet. 2007 Mar 30;3(3):e45. doi: 10.1371/journal.pgen.0030045. Epub 2007 Feb 13.
3
Genetic diversity in the Chinese pangolin (Manis pentadactyla) inferred from protein electrophoresis.

本文引用的文献

1
Allelic variants in the amino-acid sequence of the alpha chain of rabbit haemoglobin.兔血红蛋白α链氨基酸序列中的等位基因变体。
Nature. 1969 Sep 20;223(5212):1270-2. doi: 10.1038/2231270a0.
2
The amino acid sequence of the beta-chains of rabbit hemoglobin.兔血红蛋白β链的氨基酸序列。
Eur J Biochem. 1970 Nov;17(1):49-55. doi: 10.1111/j.1432-1033.1970.tb01132.x.
3
Polymorphic alleles of the gene for the beta-chain of rabbit haemoglobin.兔血红蛋白β链基因的多态性等位基因。
Biochem Genet. 1994 Oct;32(9-10):343-9. doi: 10.1007/BF02426896.
Nat New Biol. 1971 Feb 3;229(5):142-3. doi: 10.1038/newbio229142a0.
4
Trnaslational variations in the amino acid sequence of the alpha-chain of rabbit hemoglobin.
Cold Spring Harb Symp Quant Biol. 1966;31:705-14. doi: 10.1101/sqb.1966.031.01.090.
5
An electrophoretically silent polymorphism for the beta chains of rabbit hemoglobin and associated polyribosome patterns.兔血红蛋白β链的一种电泳沉默多态性及相关多核糖体模式。
Genetics. 1974 Jan;76(1):99-108. doi: 10.1093/genetics/76.1.99.
6
Characterization by polyacrylamide gel electrophoresis of hemoglobins in rabbit embryo, fetus, and adult.
Anal Biochem. 1973 Oct;55(2):521-38. doi: 10.1016/0003-2697(73)90141-3.
7
An isoleucine-valine substitution in the beta chain of rabbit hemoglobin.兔血红蛋白β链中的异亮氨酸 - 缬氨酸替换
Biochim Biophys Acta. 1974 Jun 7;351(2):437-41. doi: 10.1016/0005-2795(74)90208-6.
8
Biochemical and genetic studies on rabbit hemoglobin. I. Electrophoretic polymorphism of the beta chain.
Biochem Genet. 1989 Dec;27(11-12):673-8. doi: 10.1007/BF02396059.
9
Separator isoelectric focusing: an improved method of protein analysis and purification.等离聚焦分离法：一种改进的蛋白质分析与纯化方法。
Anal Biochem. 1977 May 1;79(1-2):166-80. doi: 10.1016/0003-2697(77)90391-8.