药物滥用管理中的长效制剂：综述与更新
Long-acting Preparations in Substance Abuse Management: A Review and Update.
作者信息
Hegde Aditya, Singh Shubh Mohan, Sarkar Siddharth
机构信息
Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
Indian J Psychol Med. 2013 Jan;35(1):10-8. doi: 10.4103/0253-7176.112194.
Abstract
Many pharmacological approaches have been used in managing substance use disorders. Conventional pharmacological agents have relatively short durations of action which make them vulnerable to non-adherence and relapse to substance use disorder. To overcome this problem, long-acting preparations have been developed with the aim of reducing the frequency of use and hence improving adherence. This review takes a broad overview of the long-acting preparations available for the management of substance use disorders. The pharmacology, advantages and disadvantages of these preparations are discussed. Many of these preparations hold promise for improving patient outcomes.
摘要
许多药理学方法已被用于治疗物质使用障碍。传统的药理学药物作用持续时间相对较短，这使得它们容易出现不依从性以及复发为物质使用障碍。为了克服这个问题，人们开发了长效制剂，旨在减少使用频率，从而提高依从性。本综述对可用于治疗物质使用障碍的长效制剂进行了广泛概述。讨论了这些制剂的药理学、优缺点。其中许多制剂有望改善患者的治疗效果。
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