Qiao Ming-Xi, Zhang Xiao-Jun, Shuang B A, Hu Hai-Yang, Zhao Xiu-Li, Chen Da-Wei
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Yao Xue Xue Bao. 2013 Apr;48(4):477-83.
The discovery, sorting and identification methods as well as targeted drug delivery systems for cancer stem cells (CSCs) have been reviewed by consulting the recent research papers. CSCs have been believed to be responsible for the occurrence and development of chemo-resistance, leading to the failure of chemotherapy. Much progress has been made in the approaches for CSCs targeting drug delivery systems. The understanding and targeted drug delivery systems for CSCs are promising to provide an alternative for cancer therapy.
通过查阅近期的研究论文，对癌症干细胞（CSCs）的发现、分选和鉴定方法以及靶向给药系统进行了综述。人们认为CSCs是化疗耐药性发生和发展的原因，导致化疗失败。在CSCs靶向给药系统的方法方面已经取得了很大进展。对CSCs的认识和靶向给药系统有望为癌症治疗提供一种替代方案。
