Department of Radiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; Institute of Radiation Medicine, Fudan University, Shanghai 200032, China.
Institute of Radiation Medicine, Fudan University, Shanghai 200032, China.
Environ Toxicol Pharmacol. 2013 Sep;36(2):595-599. doi: 10.1016/j.etap.2013.06.006. Epub 2013 Jun 24.
Cadmium exposure may be associated with high risk of hypertension. But inconsistent results have been reported. In this study, the association of blood pressure (BP) with blood cadmium (BCd) and the possible influencing factors were investigated. A total of 181 persons (71 men and 110 women) living near a cadmium smelter participated in this study. The participants completed a questionnaire and BP, BCd and related biochemical indicators were measured. The geometric mean of BCd was 3.84μg/L and 3.32μg/L for women and men. The systolic blood pressure (SBP) and diastolic blood pressure both increased with the increasing of BCd. The BP in women was positively correlated with BCd (p<0.05). The BCd level of participants with hypertension was obvious higher (+28%) than those with normal BP. The prevalence of hypertension was increased with the increasing of BCd, in particular to women (χ(2)=3.896, p=0.048). Cadmium level in blood was associated with elevation in blood pressure, especially for women.
镉暴露可能与高血压的高风险有关。但已有报道结果不一致。在这项研究中，调查了血压（BP）与血镉（BCd）之间的关系及其可能的影响因素。共有 181 名（71 名男性和 110 名女性）居住在镉冶炼厂附近的人参加了这项研究。参与者完成了一份问卷，测量了血压、BCd 和相关生化指标。女性和男性的 BCd 几何平均值分别为 3.84μg/L 和 3.32μg/L。收缩压（SBP）和舒张压均随 BCd 的增加而增加。女性的 BP 与 BCd 呈正相关（p<0.05）。高血压患者的 BCd 水平明显高于正常血压患者（+28%）。高血压的患病率随 BCd 的增加而增加，尤其是对女性（χ(2)=3.896，p=0.048）。血镉水平与血压升高有关，尤其是对女性。
