Dartigues J-F, Foubert-Samier A, Helmer C
Inserm U897, université Bordeaux Segalen, 146, rue Léo-Saignat, 33076 Bordeaux cedex, France.
Rev Epidemiol Sante Publique. 2013 Aug;61 Suppl 3:S195-8. doi: 10.1016/j.respe.2013.04.004. Epub 2013 Jul 5.
Dementia is an age-related chronic syndrome, whose the first cause is a neurodegenerative disease: Alzheimer's disease (AD). In spite of some controversies, educational level is now considered as a major risk factor for dementia and AD. The protective effect of a high level of education could be related to a preservation of cognitive reserve and a reinforcement of brain reserve. Moreover, subjects with a high level of education have a better access to health care and a better management of vascular risk factors. With the general improvement of the educational level, the age-related incidence of AD and dementia should decrease in the future.
痴呆是一种与年龄相关的慢性综合征,其首要病因是神经退行性疾病:阿尔茨海默病(AD)。尽管存在一些争议,但教育水平现在被认为是痴呆和AD的主要危险因素。高教育水平的保护作用可能与认知储备的保存和脑储备的增强有关。此外,受过高等教育的人能更好地获得医疗保健,并能更好地管理血管危险因素。随着教育水平的普遍提高,未来AD和痴呆的年龄相关发病率应该会下降。