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在澳大利亚农村地区进行的家庭药物审查中发现的与药物相关的问题。

Medication-related problems identified in home medicines reviews conducted in an Australian rural setting.

作者信息

Alderman Christopher Paul, Kong Lesley, Kildea Lindley

机构信息

Pharmacy Department, Repatriation General Hospital, South Australia, Australia.

出版信息

Consult Pharm. 2013 Jul;28(7):432-42. doi: 10.4140/TCP.n.2013.432.

DOI:10.4140/TCP.n.2013.432
PMID:23835461
Abstract

OBJECTIVE

To analyze the prevalence, nature, and patterns of medication-related problems (MRPs) and to explore relationships between these and the patterns of medication usage and clinical characteristics of the patients for whom Home Medicines Reviews (HMRs) were provided.

DESIGN

Retrospective analysis of 100 HMR reports. MRPs were grouped according to class. Analysis of medication usage patterns was undertaken using standard systems for classification of therapeutic actions and dosage intensity.

SETTING

In Australia, accredited pharmacists conduct HMRs through the federally funded HMR program, aiming to detect and prevent or resolve MRPs.

INTERVENTIONS

This study analyzed HMR reports for a cohort of home-dwelling patients living in a small rural community in South Australia.

MAIN OUTCOME MEASURE

MRPs were characterized and analyzed by drug class and dosage intensity.

RESULTS

130 MRPs were identified in 73 patients (mean ± standard deviation: 1.30 ± 1.22 per patient). The most common types of problems were an untreated indication for treatment and failure to receive medication (both n = 23), followed by adverse drug events (n = 21), drugdrug interactions, and improper drug selection (n = 19). Cardiovascular, central nervous system, and musculoskeletal agents were the classes most frequently associated with MRPs.

CONCLUSION

Medication-usage patterns were similar to those observed in previous research conducted in urban settings, both in Australia and internationally. The findings lend further support for an expanded role for pharmacists in the primary health care system, suggesting that HMRs and the medication review process can improve medication use and overall patient health outcomes.

摘要

目的

分析药物相关问题(MRP)的患病率、性质和模式,并探讨这些问题与接受居家药物评估(HMR)的患者的用药模式及临床特征之间的关系。

设计

对100份HMR报告进行回顾性分析。MRP按类别分组。使用治疗作用分类和剂量强度的标准系统对用药模式进行分析。

背景

在澳大利亚,经认可的药剂师通过联邦资助的HMR项目开展居家药物评估,旨在检测、预防或解决MRP。

干预措施

本研究分析了居住在南澳大利亚一个小乡村社区的居家患者队列的HMR报告。

主要观察指标

通过药物类别和剂量强度对MRP进行特征描述和分析。

结果

在73例患者中识别出130个MRP(均值±标准差:每位患者1.30±1.22个)。最常见的问题类型是未治疗的适应证和未用药(均为n = 23),其次是药物不良事件(n = 21)、药物相互作用和药物选择不当(n = 19)。心血管药物、中枢神经系统药物和肌肉骨骼药物是与MRP最常相关的药物类别。

结论

用药模式与之前在澳大利亚和国际城市环境中进行的研究中观察到的模式相似。这些发现进一步支持了药剂师在初级卫生保健系统中扩大作用,表明HMR和药物评估过程可以改善用药情况和患者总体健康结局。

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