Sharma C P, Sunny M C
Biosurface Technology Division, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Poojapura, Trivandrum, India.
Biomaterials. 1990 May;11(4):255-7. doi: 10.1016/0142-9612(90)90006-c.
The changes in protein adsorption onto aluminium surfaces coated with different thicknesses of oxide layers were examined. The oxide layers on aluminium substrates were derived by the anodizing technique. Protein adsorption studies were conducted using 125I-labelled albumin and the amount of albumin adsorbed was estimated with the help of a gamma counter. An increase in albumin adsorption was observed on oxide layer coated aluminium surfaces. The effect of anti-Hageman factor on albumin and fibrinogen adsorption on to bare aluminium, oxide layer coated aluminium and bare polyether urethane urea surfaces was also investigated. It was observed that the presence of anti-Hageman factor increased the adsorption of albumin and fibrinogen on to all these substrates.
研究了蛋白质在涂覆有不同厚度氧化层的铝表面上的吸附变化。铝基底上的氧化层通过阳极氧化技术制备。使用¹²⁵I标记的白蛋白进行蛋白质吸附研究，并借助γ计数器估算白蛋白的吸附量。在涂覆有氧化层的铝表面上观察到白蛋白吸附增加。还研究了抗哈格曼因子对白蛋白和纤维蛋白原在裸铝、涂覆有氧化层的铝以及裸聚醚聚氨酯脲表面上吸附的影响。观察到抗哈格曼因子的存在增加了白蛋白和纤维蛋白原在所有这些基底上的吸附。
