Low J A, Pancham S R, Worthington D, Boston R W
Am J Obstet Gynecol. 1975 Feb 15;121(4):446-51. doi: 10.1016/0002-9378(75)90072-1.
The maternal and fetal acid-base, lactate, and pyruvate characteristics during the course of labor and at delivery were studied in 124 patients delivered of an infant with evidence of metabolic acidosis at delivery. This metabolic acidosis is principally caused by hyperlactatemia resulting from the tissue oxygen debt accompanying fetal asphyxia. Hypoxemia was one mechanism contributing to this fetal asphyxia and tissue oxygen debt. This evidence of fetal asphyxia developed during the last half and principally during the last two hours of the intrapartum period. Acid-base assessment of fetal blood with identification of a metabolic acidosis will provide an accurate objective diagnosis of intrapartum fetal asphyxia.
对124例分娩时婴儿有代谢性酸中毒证据的产妇，研究了产程中和分娩时母胎的酸碱、乳酸和丙酮酸特征。这种代谢性酸中毒主要由胎儿窒息伴有的组织氧债导致的高乳酸血症引起。低氧血症是导致这种胎儿窒息和组织氧债的一种机制。这种胎儿窒息的证据在产程后半期出现，主要在产程最后两小时。通过对胎儿血液进行酸碱评估并确定代谢性酸中毒，将能准确客观地诊断产时胎儿窒息。
