女性慢性应激与性功能。
Chronic stress and sexual function in women.
机构信息
Department of Psychology, University of Texas at Austin, Austin, TX, USA.
出版信息
J Sex Med. 2013 Oct;10(10):2443-54. doi: 10.1111/jsm.12249. Epub 2013 Jul 10.
INTRODUCTION
Chronic stress is known to have negative effects on reproduction, but little is known about how it affects the sexual response cycle. The present study examined the relationship between chronic stress and sexual arousal and the mechanisms that mediate this relationship.
AIM
The aim of this study is to test the relationship between chronic stress and sexual arousal and identify mechanisms that may explain this relationship. We predicted that women experiencing high levels of chronic stress would show lower levels of genital arousal and dehydroepiandrosterone (DHEAS) and higher levels of cortisol and cognitive distraction compared with women with average levels of stress.
METHODS
Women who were categorized as high in chronic stress (high stress group; n=15) or average in chronic stress (average stress group; n=15) provided saliva samples and watched an erotic film while having their genital and psychological arousal measured.
MAIN OUTCOME MEASURES
Main outcome measures were vaginal pulse amplitude, psychological arousal, salivary cortisol, salivary DHEAS, and heart rate and compared them between women with high and average levels of chronic stress.
RESULTS
Women in the high stress group had lower levels of genital, but not psychological arousal, had higher levels of cortisol, and reported more distraction during the erotic film than women in the average stress group. The main predictor of decreased genital sexual arousal was participants' distraction scores.
CONCLUSIONS
High levels of chronic stress were related to lower levels of genital sexual arousal. Both psychological (distraction) and hormonal (increased cortisol) factors were related to the lower levels of sexual arousal seen in women high in chronic stress, but distraction was the only significant predictor when controlling for other variables.
简介
慢性应激已知对生殖有负面影响，但对于它如何影响性反应周期知之甚少。本研究检查了慢性应激与性唤起之间的关系以及介导这种关系的机制。
目的
本研究旨在测试慢性应激与性唤起之间的关系，并确定可能解释这种关系的机制。我们预测，与压力水平中等的女性相比，经历高水平慢性应激的女性的生殖器唤起和脱氢表雄酮（DHEAS）水平较低，皮质醇水平和认知分心较高。
方法
将被归类为慢性应激水平高（高应激组；n=15）或平均慢性应激水平（平均应激组；n=15）的女性提供唾液样本，并观看色情电影，同时测量其生殖器和心理唤起。
主要观察指标
主要观察指标为阴道脉搏振幅、心理唤起、唾液皮质醇、唾液 DHEAS 以及心率，并将其与慢性应激水平较高和较低的女性进行比较。
结果
高应激组女性的生殖器唤起水平较低，但心理唤起水平没有差异，皮质醇水平较高，并且在观看色情电影时报告的分心程度高于平均应激组女性。生殖器性唤起降低的主要预测因素是参与者的分心分数。
结论
高水平的慢性应激与生殖器性唤起水平降低有关。心理（分心）和激素（皮质醇增加）因素都与慢性应激水平较高的女性较低的性唤起有关，但在控制其他变量时，分心是唯一显著的预测因素。
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