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评估诺德生长素FlexPro对接受重组人生长激素治疗的儿科患者的用户友好性:一项开放标签用户调查的结果。

Assessment of user-friendliness of the Norditropin FlexPro for pediatric patients treated with recombinant human growth hormone: results of an open-label user survey.

作者信息

Adachi Masanori

出版信息

J Pediatr Endocrinol Metab. 2013;26(11-12):1105-10. doi: 10.1515/jpem-2013-0071.

DOI:10.1515/jpem-2013-0071
PMID:23843576
Abstract

OBJECTIVE

To assess the user-friendliness of the Norditropin FlexPro (Novo Nordisk A/S, Bagsvaerd, Denmark), a newly developed growth hormone (GH) injection pen.

METHODS

This study consisted of a single-center, single-arm, open-label, questionnaire based survey of patients undergoing GH treatment for diverse indications who were scheduled to switch from the formerly used device Norditropin NordiFlex (Novo Nordisk A/S) to the FlexPro and evaluate each device's usability.

RESULTS

A total of 82 patients participated in the study. Compared to the NordiFlex, the FlexPro was regarded as easier to grip, easier to hold during injection, and more stable during injection. The degree of pain at insertion perceived by the patient and the patient's fear of injection were significantly decreased when using the FlexPro, and 81% of the respondents selected the FlexPro as the more preferable device.

CONCLUSIONS

The FlexPro was more user-friendly than the NordiFlex. Perception of pain at insertion and fear of injection were lessened by using the FlexPro.

摘要

目的

评估新开发的生长激素(GH)注射笔诺和锐(丹麦 Bagsvaerd 的诺和诺德公司)的用户友好性。

方法

本研究为单中心、单臂、开放标签、基于问卷的调查,对象为因各种适应症接受 GH 治疗且计划从以前使用的诺和笔更换为诺和锐的患者,并评估每种设备的易用性。

结果

共有 82 名患者参与研究。与诺和笔相比,诺和锐被认为更容易握持、注射时更易于拿稳且注射过程中更稳定。使用诺和锐时患者在注射时感觉到的疼痛程度以及对注射的恐惧显著降低,81% 的受访者选择诺和锐作为更优的设备。

结论

诺和锐比诺和笔对用户更友好。使用诺和锐可减轻对注射时疼痛的感知以及对注射的恐惧。

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Assessment of user-friendliness of the Norditropin FlexPro for pediatric patients treated with recombinant human growth hormone: results of an open-label user survey.评估诺德生长素FlexPro对接受重组人生长激素治疗的儿科患者的用户友好性:一项开放标签用户调查的结果。
J Pediatr Endocrinol Metab. 2013;26(11-12):1105-10. doi: 10.1515/jpem-2013-0071.
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Patient preference for a new growth hormone injection device: results of an open-label study in Japanese pediatric patients.日本儿科患者对新型生长激素注射装置的患者偏好:一项开放标签研究的结果
J Pediatr Endocrinol Metab. 2011;24(7-8):489-96. doi: 10.1515/jpem.2011.252.
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Children and adolescent acceptability of a new device system to administer human growth hormone--a pilot study.一种新型人生长激素给药装置系统在儿童和青少年中的可接受性——一项试点研究。
J Pediatr Endocrinol Metab. 2012;25(3-4):285-94. doi: 10.1515/jpem-2011-0395.
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User assessment of Norditropin NordiFlex(®), a new prefilled growth hormone pen: a Phase IV multicenter prospective study.新型预填充生长激素笔Norditropin NordiFlex(®)的用户评估:一项IV期多中心前瞻性研究。
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