Cesarman-Maus Gabriela, Meillón Luis, Volkow Patricia, Vargas-Ruiz Angel Gabriel, Cornejo Patricia, López-Navarro Omar, Moreno María Cruz, Coronel Omar, García-Fernandez Laura, Ochoa-Carrillo Francisco Javier, Siñani Marianela, Baz Patricia, Izaguirre Raúl
Clínica de Cancer y Trombosis, Departamento de Hematología, Instituto Nacional de Cancerología.
Rev Invest Clin. 2013 Mar-Apr;65(2):174-82.
Individuals with cancer are at increased risk of developing thrombosis. The prevalence of thrombosis depends on tumor-related factors such as histological type, stage, the use of central venous catheters, or treatment with surgery, chemotherapy or radiotherapy, as well as general prothrombotic factors including advanced age, immobility, obesity, hereditary thrombophilias and comorbidities. Prophylactic or therapeutic treatment of thrombosis should be individualized and will depend on both the risk of thrombosis and bleeding. In this review we intend to update concepts that have changed substantially such as green food-free diet, or the indication of absolute bed rest in patients with recent thrombosis. We propose evidence-based therapeutic strategies regarding the most prevalent clinical problems encountered in patients with cancer and thrombosis.
癌症患者发生血栓形成的风险增加。血栓形成的患病率取决于肿瘤相关因素，如组织学类型、分期、中心静脉导管的使用，或手术、化疗或放疗治疗，以及一般的促血栓形成因素，包括高龄、活动减少、肥胖、遗传性血栓形成倾向和合并症。血栓形成的预防性或治疗性治疗应个体化，并将取决于血栓形成和出血的风险。在本综述中，我们打算更新一些已发生重大变化的概念，如无绿色食物饮食，或近期发生血栓形成患者绝对卧床休息的指征。我们针对癌症和血栓形成患者中最常见的临床问题提出基于证据的治疗策略。
