Department of Radiology, Cork University Hospital, Wilton, Cork, Ireland.
Clin Imaging. 2013 Sep-Oct;37(5):821-9. doi: 10.1016/j.clinimag.2013.04.005. Epub 2013 Jul 9.
In an era of molecular targeted therapy, patients with advanced gastrointestinal stromal tumor (GIST) are living longer and are often followed with imaging. Therefore, it is important for the radiologists to be aware of the atypical subtypes of GIST, implications of molecular makeup, its behavior, and the uncommon metastatic sites. The aim of this pictorial review is to illustrate the lesser-known aspects of GIST including histological and molecular classifications, syndromes associated with GIST, and uncommon metastatic sites.
在分子靶向治疗时代,晚期胃肠道间质瘤(GIST)患者的生存期延长,且常需要进行影像学随访。因此,放射科医生了解 GIST 的非典型亚型、分子构成的意义、其行为以及罕见的转移部位非常重要。本影像学综述的目的在于阐述 GIST 的一些鲜为人知的方面,包括组织学和分子分类、与 GIST 相关的综合征以及罕见的转移部位。