Central Veterinary Research Laboratory, PO Box 597, Dubai, United Arab Emirates.
Vet Parasitol. 2013 Oct 18;197(1-2):176-81. doi: 10.1016/j.vetpar.2013.06.015. Epub 2013 Jun 22.
Equine habronematidosis has a global distribution and is caused by three spirurid species, Habronema muscae, Habronema microstoma and Draschia megastoma. A case of cutaneous habronematidosis in a stallion in a stable in Dubai, UAE gave occasion to investigate the parasite situation on the farm. Patent H. muscae infections were diagnosed in 18 out of 49 horses in a stable in Dubai, UAE with a xenodiagnostic test using houseflies as indicator host. All horses in the stable were treated with a single dose of moxidectin administered orally as 2% gel in a dosage of 0.4 mg/kg body weight and the efficacy of this targeted treatment was studied. Habronema infection was terminated in all horses. A fly survey conducted at the farm prior and after treatment revealed two muscid species: Musca domestica and Stomoxys calcitrans. Only M. domestica caught at the farm showed a natural infection with Habronema larvae prior and shortly after anthelmintic treatment. Later, examination of flies caught at the farm in monthly intervals up to the end of observation (8 months after treatment) gave negative results. The absence of infection in the intermediate host was an indication of the eradication of stomach worms. The described xenodiagnostic test is a useful tool to diagnose H. muscae infections and can be used to evaluate the efficacy of nematocides in equines.
马胃蝇蛆病分布广泛，由三种旋尾目线虫引起，即马胃蝇蛆、微小胃蝇蛆和巨型胃蝇蛆。在阿联酋迪拜的一个马厩中，一匹种马患有皮肤胃蝇蛆病，这为调查农场中的寄生虫情况提供了契机。利用家蝇作为指示宿主进行的异种诊断试验在阿联酋迪拜的一个马厩中确诊了 49 匹马中的 18 匹患有马胃蝇蛆病。所有马匹均采用口服 2%凝胶（剂量为 0.4mg/kg 体重）的莫昔克丁进行单次治疗，研究了这种靶向治疗的效果。所有马匹的胃蝇蛆感染均被终止。在治疗前后，对农场进行了苍蝇调查，发现了两种蝇科物种：家蝇和厩螫蝇。仅在农场捕获的家蝇在驱虫治疗前后显示出与旋尾目幼虫的自然感染。随后，在观察结束前（驱虫治疗后 8 个月）每月对农场捕获的苍蝇进行检查，结果均为阴性。中间宿主无感染表明胃线虫已被根除。所描述的异种诊断试验是诊断马胃蝇蛆感染的有用工具，可用于评估抗线虫药物在马中的疗效。
