Gastroenterology, Hepatology and Nutrition, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock AR 72202, USA.
J Pediatr Surg. 2013 Jun;48(6):E1-3. doi: 10.1016/j.jpedsurg.2013.04.011.
Intestinal failure (IF) results from a critical reduction in the functional intestinal mass resulting in dependence on total parenteral nutrition (TPN) for growth and survival. Short bowel syndrome (SBS) is the most common cause of intestinal failure in pediatrics. Following resection, the small bowel undergoes adaptation, a process wherein the bowel elongates and dilates in order to increase intestinal absorptive capacity. Small bowel dilatation can lead to dysmotility and small bowel bacterial overgrowth which may further enhance feeding intolerance. Bowel lengthening procedures are beneficial when there is significant dilatation of the small bowel and subsequent inability to advance enteral feeds. We describe a patient with intestine failure and short bowel syndrome due to gastroschisis who, presented with anemia and occult gastrointestinal bleeding, following Serial Transverse Enteroplasty procedure (STEP). Video capsule endoscopy (VCE) revealed multiple ulcerations at surgical staple sites throughout the distal 2/3 of the remaining small intestine which were the likely source of intestinal blood loss.
肠衰竭(IF)是由于功能性肠段严重减少,导致患儿生长和生存依赖全胃肠外营养(TPN)。短肠综合征(SBS)是儿科肠衰竭最常见的原因。小肠切除术后,小肠会发生适应性改变,即肠管伸长和扩张,以增加肠道吸收能力。小肠扩张可导致运动障碍和小肠细菌过度生长,这可能进一步加重喂养不耐受。当小肠明显扩张且随后无法推进肠内喂养时,肠延长术是有益的。我们描述了一位因先天性腹裂导致肠衰竭和短肠综合征的患者,该患者在接受连续横结肠成形术(STEP)后出现贫血和隐匿性胃肠道出血。视频胶囊内镜(VCE)显示在剩余小肠的远端 2/3 处的手术吻合部位有多处溃疡,这可能是肠道出血的来源。