Centre for Health Behaviours Research, The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.
Vaccine. 2013 Sep 23;31(41):4675-81. doi: 10.1016/j.vaccine.2013.06.090. Epub 2013 Jul 8.
Men who have sex with men (MSM) are at high risk of contracting HIV and developing genital warts and penile/anal cancers. HPV vaccines are efficacious in preventing such HPV-related diseases among males and WHO recommends its use to young MSM. In a cross-sectional survey, 542 MSM were interviewed. After being briefed about the vaccines' efficacies and the market price, the prevalence of acceptability of HPV vaccination was 29.2%. Adjusted by significant background variables, perceived high/very high chances of contracting genital warts [adjusted odds ratio (AOR)=2.04, 95%CI=1.11-3.72] and penile/anal cancers (AOR=1.89, 95%CI=1.09-3.29) among local MSM, perceived moderately high mortality rate of penile/anal cancers (AOR=1.78, 95%CI=1.13-2.81), fear toward penile/anal cancers (moderate: AOR=1.75, 95%CI=1.07-2.86; high/very high: AOR=1.82, 95%CI=1.13-2.92) and disagreement with the statement "MSM in general are not willing to take HPV vaccines" (AOR=1.82, 95%CI=1.24-2.68) were associated with the conditional acceptability. Acceptability of this new measure is reasonably high and there are rooms for improvement. Implementation trials to promote HPV vaccination by changing cognitions such as HPV-related risk perceptions, norms and perceptions toward anal/penile cancer are greatly warranted.
男男性行为者(MSM)感染艾滋病毒和患上生殖器疣、阴茎/肛门癌的风险很高。HPV 疫苗在预防男性 HPV 相关疾病方面具有疗效,世卫组织建议为年轻 MSM 使用该疫苗。在一项横断面调查中,对 542 名 MSM 进行了访谈。在简要介绍了疫苗的疗效和市场价格后,HPV 疫苗接种的可接受性流行率为 29.2%。经显著背景变量调整后,本地 MSM 认为感染生殖器疣的几率高/非常高(调整后的优势比[OR]为 2.04,95%CI=1.11-3.72)和阴茎/肛门癌(OR=1.89,95%CI=1.09-3.29)、认为阴茎/肛门癌的死亡率较高(中度:OR=1.78,95%CI=1.13-2.81)、对阴茎/肛门癌感到恐惧(中度:OR=1.75,95%CI=1.07-2.86;高/非常高:OR=1.82,95%CI=1.13-2.92)以及不同意“一般来说 MSM 不愿意接种 HPV 疫苗”(OR=1.82,95%CI=1.24-2.68),这些都与条件可接受性有关。这种新措施的可接受性相当高,还有改进的空间。为了提高 HPV 疫苗接种的可接受性,需要开展实施试验来改变 HPV 相关风险认知、规范和对肛门/阴茎癌的认知等。