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一只猫的胆道癌肉瘤

Carcinosarcoma of the biliary system in a cat.

作者信息

Cavicchioli Laura, Ferro Silvia, Callegari Carolina, Auriemma Edoardo, Zini Eric, Zappulli Valentina

机构信息

1Laura Cavicchioli, Department of Comparative Biomedicine and Food Sciences, University of Padova, Viale dell'Università 16, 35020 Legnaro (PD), Italy.

出版信息

J Vet Diagn Invest. 2013 Sep;25(5):562-5. doi: 10.1177/1040638713495389. Epub 2013 Jul 11.

Abstract

A 12-year-old, mixed-breed domestic cat was diagnosed with a multicystic hepatic mass via ultrasonographic examination and computer tomography scan. The tumor associated with the left medial liver lobe, and connected by a thin stalk to the hilar region, was surgically removed. The mass was firm, encapsulated, mottled white to red black, multinodular, and cystic. Histologic diagnosis was carcinosarcoma supported by positive immunohistochemistry for cytokeratins and vimentin of atypical neoplastic cell populations. On the basis of morphology, the origin was considered to be in the biliary tract. Biliary carcinosarcoma is a rare neoplasm that occurs in people. The epidemiology and risk factors have not yet been determined, and the prognosis is poor except for cases in which curative resection is performed.

摘要

一只12岁的混种家猫经超声检查和计算机断层扫描被诊断为多囊性肝脏肿块。与左内侧肝叶相关联、通过细蒂与肝门区域相连的肿瘤被手术切除。该肿块质地坚硬,有包膜,呈斑驳的白色至红黑色,多结节且为囊性。组织学诊断为癌肉瘤,非典型肿瘤细胞群的细胞角蛋白和波形蛋白免疫组化呈阳性支持该诊断。基于形态学,其起源被认为是在胆道。胆管癌肉瘤是一种在人类中发生的罕见肿瘤。其流行病学和危险因素尚未确定,除了进行根治性切除的病例外,预后较差。

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