Dowdle S C, Human D G, Mann M D
Department of Paediatrics and Child Health, University of Cape Town, South Africa.
J Nucl Med. 1990 Aug;31(8):1276-9.
Xenon-133 lung ventilation and perfusion scans were done preoperatively after cardiac catheterization and cineangiocardiography in 19 children; 6 had pulmonary atresia with an intact ventricular septum and hypoplastic right ventricle, 4 pulmonary atresia with associated complex univentricular heart, and 9 extreme Tetralogy of Fallot. The four patients with discrepancies in the sizes of the left and right pulmonary arteries on angiography had marked asymmetry of pulmonary perfusion and ventilation-perfusion imbalance on scintigraphy. Similar degrees of asymmetry and imbalance were present in 6 of the 15 children with equal-size pulmonary vessels. Asymmetry of pulmonary perfusion and ventilation-perfusion imbalance were associated with a poor prognosis.
19名儿童在术前进行了心脏导管插入术和心血管造影术后接受了氙-133肺通气和灌注扫描；其中6例为室间隔完整和右心室发育不全的肺动脉闭锁，4例为伴有复杂单心室心脏的肺动脉闭锁，9例为极重度法洛四联症。血管造影显示左右肺动脉大小存在差异的4例患者，其肺灌注明显不对称，闪烁扫描显示通气-灌注失衡。15例肺血管大小相等的儿童中，有6例存在类似程度的不对称和失衡。肺灌注不对称和通气-灌注失衡与预后不良相关。
