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传统经支气管针吸活检术的学习曲线

Learning curve of conventional transbronchial needle aspiration.

作者信息

Tutar Nuri, Büyükoğlan Hakan, Yılmaz Insu, Kanbay Asiye, Onal Omer, Bilgin Mehmet, Canöz Ozlem, Demir Ramazan, Oyak Fatma Sema, Gülmez Inci, Cetinkaya Erdoğan

机构信息

Department of Pulmonary Medicine, School of Medicine, Erciyes University, Kayseri, Turkey.

出版信息

Clin Respir J. 2014 Jan;8(1):79-85. doi: 10.1111/crj.12041. Epub 2013 Oct 1.

DOI:10.1111/crj.12041
PMID:23848482
Abstract

BACKGROUND AND AIMS

Intrathoracic lymphadenopathy usually occurs as a result of neoplasm, granulomatous diseases, infections or reactive hyperplasia. Conventional transbronchial needle aspiration (C-TBNA) is a cheap and safe procedure for diagnosing intrathoracic lymphadenopathy. The aim of this study was to assess the learning curve and diagnostic accuracy of C-TBNA after an observational education programme.

METHODS

In the present study, we retrospectively evaluated our first 62 C-TBNA procedures at Erciyes University between May 2012 and December 2012 after an observational education programme. The first 31 patients were defined as group A, and the second 31 patients as group B.

RESULTS

One hundred and seven lymph nodes were sampled in 62 patients by C-TBNA. Adequate lymph node samples were obtained in 52 of the 62 patients (83.8%). In these 52 patients, two patients had a diagnosis of 'suspicious of malignancy' by C-TBNA, and these patients were excluded from the analysis. In the remaining 50 cases who had adequate results, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy per patient were 80.6%, 92.9%, 96.7%, 65.0% and 84.0%, respectively. The diagnostic accuracy rates of C-TBNA for Group A and B were 72.0% (18/25) and 96.0% (24/25), and the difference was statistically significant (P < 0.05).

CONCLUSION

C-TBNA is a useful diagnostic procedure for sampling intrathoracic lymphadenopathies and masses that are adjacent to the bronchial system. An observational education programme is helpful for learning C-TBNA. The diagnostic yield improves in time, and approximately 30 procedures may be sufficient to achieve successful results.

摘要

背景与目的

胸内淋巴结肿大通常由肿瘤、肉芽肿性疾病、感染或反应性增生引起。传统经支气管针吸活检术(C-TBNA)是诊断胸内淋巴结肿大的一种廉价且安全的方法。本研究的目的是评估在一项观察性教育计划后C-TBNA的学习曲线和诊断准确性。

方法

在本研究中,我们回顾性评估了2012年5月至2012年12月在埃尔西耶斯大学进行的前62例C-TBNA手术,这些手术是在一项观察性教育计划之后进行的。前31例患者被定义为A组,后31例患者被定义为B组。

结果

62例患者通过C-TBNA对107个淋巴结进行了采样。62例患者中有52例(83.8%)获得了足够的淋巴结样本。在这52例患者中,2例患者通过C-TBNA诊断为“可疑恶性肿瘤”,这2例患者被排除在分析之外。在其余50例结果足够的病例中,每位患者的敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)和诊断准确性分别为80.6%、92.9%、96.7%、65.0%和84.0%。A组和B组C-TBNA的诊断准确率分别为72.0%(18/25)和96.0%(24/25),差异有统计学意义(P < 0.05)。

结论

C-TBNA是一种用于对支气管系统附近的胸内淋巴结肿大和肿块进行采样的有用诊断方法。一项观察性教育计划有助于学习C-TBNA。诊断率会随着时间提高,大约30次手术可能足以取得成功结果。

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