Department of Surgery, Kyorin University School of Medicine, Tokyo, Japan; Department of Thoracic Surgery, Gunma Prefectural Cancer Center, Gunma, Japan.
Clin Imaging. 2013 Sep-Oct;37(5):876-83. doi: 10.1016/j.clinimag.2013.06.001. Epub 2013 Jul 10.
The purpose of the study was to retrospectively characterize diffusion-weighted magnetic resonance imaging (DWI) and positron emission tomography for differentiating among the various cytological subtypes of primary lung adenocarcinomas. The maximum diffusion signal intensities and the maximum standardized uptake value (SUV max) of 31 lesions were analyzed after delineation of regions of interest on the images. Diffusion intensities were 0.934 for Clara type, 0.938 for type II type, 1.473 for nongoblet type, and 1.617 for poorly differentiated adenocarcinoma type based on Shimosato's cytological classification (P=.020). The SUV max values were 4.926, 5.491, 5.709, and 12.132, respectively (P=.044). DWI might reflect some of the cytological characteristics of the tumor cells for differentiating the subtypes of lung adenocarcinomas.
本研究旨在通过回顾性分析，探讨扩散加权磁共振成像（DWI）与正电子发射断层扫描（PET）在鉴别原发性肺腺癌不同细胞亚型中的作用。对 31 个病灶的图像进行感兴趣区域勾画后，分析病灶的最大扩散信号强度和最大标准化摄取值（SUV max）。基于 Shimosato 的细胞学分类，Clara 型的弥散强度为 0.934，II 型为 0.938，非杯状型为 1.473，低分化腺癌型为 1.617（P=.020）。SUV max 值分别为 4.926、5.491、5.709 和 12.132（P=.044）。DWI 可能反映了肿瘤细胞的某些细胞学特征，有助于鉴别肺腺癌的亚型。
