静息状态下前额叶皮质近红外光谱数据分析的新方法。

New method of analyzing NIRS data from prefrontal cortex at rest.

机构信息

Department of Electrical Engineering and Bioscience, Waseda University, Tokyo, Japan.

Department of Neurological Surgery, Division of Optical Brain Engineering, Nihon University School of Medicine, Tokyo, Japan.

出版信息

Adv Exp Med Biol. 2013;789:391-397. doi: 10.1007/978-1-4614-7411-1_52.

DOI:10.1007/978-1-4614-7411-1_52

PMID:23852520

Abstract

The aim of this study was to develop a simple technique for objective assessment of mental stress levels by measuring hemoglobin concentration changes in the bilateral prefrontal cortex (PFC) at rest, employing two-channel near-infrared spectroscopy (NIRS). Each subject was instructed to think about nothing in particular for 3 min and then to complete the State-Trait Anxiety Inventory (STAI) test. Next, NIRS measurements were taken and the left/right asymmetry of PFC activity at rest was evaluated by calculating the proposed Laterality Index at Rest (LIR). There was a significant positive correlation between the LIR and STAI score in 39 subjects. The present method allowed evaluation of mental stress level from NIRS data in the PFC at rest.

摘要

本研究旨在通过双道近红外光谱（NIRS）测量静息时双侧前额叶皮质（PFC）中的血红蛋白浓度变化，开发一种简单的技术来客观评估精神应激水平。每位受试者被要求在 3 分钟内什么都不想，然后完成状态-特质焦虑量表（STAI）测试。接下来，进行 NIRS 测量，并通过计算静息时提出的侧化指数（LIR）来评估 PFC 静息时的活动左右不对称性。在 39 名受试者中，LIR 与 STAI 评分之间存在显著正相关。本方法允许从 PFC 的 NIRS 数据评估静息时的精神应激水平。