Division of Biomedical Informatics, UCSD, , San Diego, California, USA.
BMJ Qual Saf. 2013 Oct;22 Suppl 2(Suppl 2):ii40-ii51. doi: 10.1136/bmjqs-2013-001884. Epub 2013 Jul 13.
Health information technology (HIT) systems have the potential to reduce delayed, missed or incorrect diagnoses. We describe and classify the current state of diagnostic HIT and identify future research directions.
A multi-pronged literature search was conducted using PubMed, Web of Science, backwards and forwards reference searches and contributions from domain experts. We included HIT systems evaluated in clinical and experimental settings as well as previous reviews, and excluded radiology computer-aided diagnosis, monitor alerts and alarms, and studies focused on disease staging and prognosis. Articles were organised within a conceptual framework of the diagnostic process and areas requiring further investigation were identified.
HIT approaches, tools and algorithms were identified and organised into 10 categories related to those assisting: (1) information gathering; (2) information organisation and display; (3) differential diagnosis generation; (4) weighing of diagnoses; (5) generation of diagnostic plan; (6) access to diagnostic reference information; (7) facilitating follow-up; (8) screening for early detection in asymptomatic patients; (9) collaborative diagnosis; and (10) facilitating diagnostic feedback to clinicians. We found many studies characterising potential interventions, but relatively few evaluating the interventions in actual clinical settings and even fewer demonstrating clinical impact.
Diagnostic HIT research is still in its early stages with few demonstrations of measurable clinical impact. Future efforts need to focus on: (1) improving methods and criteria for measurement of the diagnostic process using electronic data; (2) better usability and interfaces in electronic health records; (3) more meaningful incorporation of evidence-based diagnostic protocols within clinical workflows; and (4) systematic feedback of diagnostic performance.
健康信息技术(HIT)系统具有减少延迟、遗漏或错误诊断的潜力。我们描述并分类了当前诊断 HIT 的状态,并确定了未来的研究方向。
使用 PubMed、Web of Science、回溯和前向参考文献搜索以及领域专家的贡献进行了多方面的文献搜索。我们包括在临床和实验环境中评估的 HIT 系统以及以前的综述,并排除了放射学计算机辅助诊断、监测警报和报警,以及专注于疾病分期和预后的研究。文章按照诊断过程的概念框架进行组织,并确定了需要进一步研究的领域。
确定了 HIT 方法、工具和算法,并将其组织成与以下方面相关的 10 个类别:(1)信息收集;(2)信息组织和显示;(3)鉴别诊断生成;(4)诊断权重;(5)诊断计划生成;(6)获取诊断参考信息;(7)促进随访;(8)无症状患者的早期检测筛查;(9)协作诊断;(10)促进诊断反馈给临床医生。我们发现许多研究都在描述潜在的干预措施,但只有少数研究评估了实际临床环境中的干预措施,甚至更少的研究证明了临床影响。
诊断 HIT 研究仍处于早期阶段,几乎没有证明具有可衡量的临床影响。未来的努力需要集中在以下几个方面:(1)使用电子数据改进测量诊断过程的方法和标准;(2)改善电子健康记录中的可用性和界面;(3)更有意义地将基于证据的诊断协议纳入临床工作流程中;(4)系统地反馈诊断性能。