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缺氧缺血性脑病后的反射性痴笑-泪腺性癫痫发作。

Reflex gelastic-dacrystic seizures following hypoxic-ischaemic encephalopathy.

作者信息

Verma Rajesh, Praharaj Heramba Narayan

机构信息

Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, India.

出版信息

BMJ Case Rep. 2013 Jul 12;2013:bcr2013010506. doi: 10.1136/bcr-2013-010506.

Abstract

Reflex or stimulus-sensitive epilepsies are uncommon epileptic syndromes triggered by exogenous-specific sensory stimulus or endogenous various mental activities. Gelastic-dacrystic seizures are rare epileptic manifestations characterised by ictal laughter and crying. Gelastic-dacrystic seizures are commonly caused by hypothalamic hamartoma but rarely described due to cortical dysplasia, lesions of frontal and temporal lobes, tumours and vascular malformations. We report a young woman who presented with somatosensory-evoked gelastic-dacrystic seizures. This patient had a positive history of perinatal insult substantiated by MRI findings. Hypoxic-ischaemic encephalopathy as the cause of gelastic-dacrystic seizures has not been reported so far in the literature.

摘要

反射性或刺激敏感性癫痫是由外源性特定感觉刺激或内源性各种精神活动触发的罕见癫痫综合征。痴笑-啼哭发作是一种罕见的癫痫表现,其特征为发作性笑和哭。痴笑-啼哭发作通常由下丘脑错构瘤引起,但因皮质发育异常、额叶和颞叶病变、肿瘤及血管畸形导致的情况很少被描述。我们报告一名出现躯体感觉诱发的痴笑-啼哭发作的年轻女性。该患者有围产期损伤的阳性病史,MRI检查结果证实了这一点。迄今为止,文献中尚未报道缺氧缺血性脑病作为痴笑-啼哭发作的病因。

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