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放射治疗用磁跟踪系统。

Magnetic tracking system for radiation therapy.

出版信息

IEEE Trans Biomed Circuits Syst. 2010 Aug;4(4):223-31. doi: 10.1109/TBCAS.2010.2046737.

Abstract

Intensity-modulated radiation therapy (IMRT) requires precise delivery of the prescribed dose of radiation to the target and surrounding tissue. Irradiation of moving body anatomy is possible only if stable, accurate, and reliable information about the moving body structures are provided in real time. This paper presents a magnetic position tracking system for radiation therapy. The proposed system uses only four transmitting coils and an implantable transponder. The four transmitting coils generate a magnetic field which is sensed and measured by a biaxial magnetoresistive sensor in the transponder in the tumor. The transponder transmits the information back to a computer to determine the position of the transponder allowing it to track the tumor in real time. The transmission of the information from the transponder to the computer can be wired or wireless. Measurements using a biaxial sensor agree well with the field strength calculated from the ideal equations. The translation from the measurement data to the 3-D location and orientation requires a numerical technique because the equations are in nonclosed forms. The algorithm of tracking is implemented using MATLAB. Each calculation of the position along the target trajectory takes 30 ms, which makes the proposed system suitable for real-time tracking of the transponder for radiation assessment and delivery. An error of less than 2 mm is achieved in the demonstration.

摘要

调强放射治疗(IMRT)需要将规定剂量的辐射精确地输送到靶区和周围组织。只有在实时提供有关移动体结构的稳定、准确和可靠信息的情况下,才能对移动体解剖结构进行照射。本文介绍了一种用于放射治疗的磁场位置跟踪系统。所提出的系统仅使用四个发射线圈和一个可植入的应答器。四个发射线圈产生磁场,应答器中的双轴磁阻传感器感应并测量该磁场。应答器将信息传输回计算机,以确定应答器的位置,从而实现实时跟踪肿瘤。应答器与计算机之间的信息传输可以是有线的,也可以是无线的。使用双轴传感器的测量结果与从理想方程计算出的场强吻合得很好。由于方程是非闭合形式的,因此需要一种数值技术将测量数据转换为 3D 位置和方向。跟踪算法使用 MATLAB 实现。沿着目标轨迹的每个位置计算需要 30ms,这使得所提出的系统适合于实时跟踪应答器进行辐射评估和输送。在演示中实现了小于 2mm 的误差。

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