Mahboob Atiya, Iqbal Zafar, Javed Rabail, Taj Azeem, Munir Asma, Saleemi Munir Akhtar, Yaqub Faryal
Department of Dermatology, Shaikh Zayed Federal Postgraduate Medical Institute, Pakistan.
J Ayub Med Coll Abbottabad. 2012 Jan-Mar;24(1):52-4.
Each year dengue related infections are rising in tropical countries. There is not enough data available on dermatological manifestations of dengue fever. This study was conducted to investigate prevalence and type of dermatological manifestations of dengue fever (DF). Dengue Haemorrhagic Fever (DHF), and Dengue Shock Syndrome (DSS).
A Prospective study was contacted in Department of Medicine, Shaikh Zayed Hospital, Lahore, from 3rd Oct to 20th Nov 2010. Specific serological tests for DF were done in all 60 patients admitted with suspected diagnosis of DF, DHF or DSS. Forty-eight confirmed cases were evaluated for age, gender, mucocutaneous features and outcome of the disease.
Forty-eight out of 60 patients had positive serology for dengue fever. Male to female ratio was 1.09:1. Their ages ranged 5-68 years with a mean of 31.5 +/- 15.2. DF, DHF and DSS were found in 71%, 19% and 10% respectively. Common dermatological presentations were oral mucous membrane congestion (66.67%), generalised morbiliform rash (64.58%) and eye congestion (64.58%). Purpuric spots along with mucous membrane congestion, generalised morbiliform rash and eyes congestion was observed in 20.83%, 12.5% and 6.25% patients respectively. All except one patient improved clinically. One patient died of respiratory distress and haemorrhage on second day of admission.
Dermatological features are significantly noticeable in dengue fever patients. These may help us in early diagnosis and better management of patients.
在热带国家，每年登革热相关感染病例都在增加。关于登革热皮肤表现的数据不足。本研究旨在调查登革热（DF）、登革出血热（DHF）和登革休克综合征（DSS）皮肤表现的患病率及类型。
2010年10月3日至11月20日，在拉合尔谢赫扎耶德医院内科进行了一项前瞻性研究。对所有60例疑似诊断为DF、DHF或DSS的住院患者进行了DF的特异性血清学检测。对48例确诊病例的年龄、性别、黏膜皮肤特征及疾病转归进行了评估。
60例患者中有48例登革热血清学检测呈阳性。男女比例为1.09:1。年龄范围为5 - 68岁，平均年龄为31.5 +/- 15.2岁。DF、DHF和DSS分别占71%、19%和10%。常见的皮肤表现为口腔黏膜充血（66.67%）、全身性麻疹样皮疹（64.58%）和眼部充血（64.58%）。分别有20.83%、12.5%和6.25%的患者出现紫癜伴黏膜充血、全身性麻疹样皮疹和眼部充血。除1例患者外，所有患者临床症状均有改善。1例患者在入院第二天死于呼吸窘迫和出血。
登革热患者的皮肤特征非常明显。这些特征可能有助于我们早期诊断并更好地管理患者。
