Section of Cardiac Electrophysiology, Cardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia, PA 19004, USA.
Circ J. 2013;77(8):1957-66. doi: 10.1253/circj.cj-13-0758. Epub 2013 Jul 12.
The term "nonischemic cardiomyopathy" (NICM) designates a myocardial disease characterized by mechanical and/or electrical dysfunction in the absence of significant coronary artery disease, valvular heart disease, hypertension, or congenital heart disease. Although sustained ventricular tachycardia (VT) occurs in only 5% of patients with NICM, it is an important cause of sudden cardiac death. In this review we summarize the current understanding of the anatomic and electrophysiologic substrates of VT in the different types of NICM. In addition, we discuss recent progress and experience with catheter ablation of VT in these patients.
“非缺血性心肌病”（NICM）一词指的是一种心肌疾病，其特征为在不存在明显冠状动脉疾病、心脏瓣膜病、高血压或先天性心脏病的情况下出现机械和/或电功能障碍。尽管持续性室性心动过速（VT）仅发生在 5%的 NICM 患者中，但它是心脏性猝死的一个重要原因。在这篇综述中，我们总结了目前对不同类型 NICM 中 VT 的解剖和电生理基质的理解。此外，我们还讨论了在这些患者中应用导管消融治疗 VT 的最新进展和经验。
