免疫疗法：用于治疗1型糖尿病的修饰胰岛素原。 - Suppr

Immunotherapy: Modified proinsulin to treat T1DM.

作者信息

Geach Tim

出版信息

Nat Rev Endocrinol. 2013 Sep;9(9):503. doi: 10.1038/nrendo.2013.133. Epub 2013 Jul 16.

DOI:10.1038/nrendo.2013.133

PMID:23856817

Abstract

摘要

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Immunotherapy: Modified proinsulin to treat T1DM.

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本文引用的文献

Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes.

Sci Transl Med. 2013 Jun 26;5(191):191ra82. doi: 10.1126/scitranslmed.3006103.

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Immunotherapy: Modified proinsulin to treat T1DM.

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Immunotherapy: Modified proinsulin to treat T1DM.

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