Voiculescu V, Psatta D M
Institute of Neurology and Psychiatry, Bucharest, Romania.
Rom J Neurol Psychiatry. 1990 Apr-Jun;28(2):153-4.
A 53-year-old man developed spastic ataxia associated with diabetes insipidus. The patient experienced frequent attacks of stiffness and numbness of the four limbs accompanied by difficulty of speech. During an eight years' follow-up a progressive deterioration of the motor function was observed but no extracerebral manifestations were noticed. The association of spastic ataxia is generally considered as diagnostic of histiocytosis X. In the present case, however, multiple sclerosis seems a more likely diagnosis in view of the late onset and the highly characteristic brain stem seizures.
一名53岁男性出现了与尿崩症相关的痉挛性共济失调。患者频繁发作四肢僵硬和麻木，并伴有言语困难。在八年的随访期间，观察到运动功能进行性恶化，但未发现脑外表现。痉挛性共济失调的关联通常被认为是组织细胞增多症X的诊断依据。然而，在本病例中，鉴于发病较晚以及高度特征性的脑干发作，多发性硬化似乎是更有可能的诊断。
