一些新型D-失碳雌酮衍生物的合成及雌激素活性筛选
Synthesis and estrogen activity screening of some new D-secoestrone derivatives.
作者信息
Petrović J A, Pejanović V M, Miljković D A, Hranisavljević J T
机构信息
Institute of Chemistry, Faculty of Sciences, University of Novi Sad, Yugoslavia.
出版信息
Steroids. 1990 Jun;55(6):276-8. doi: 10.1016/0039-128x(90)90045-d.
PMID:2385852
Abstract
Five new D-secoestrone derivatives were synthesized, starting from 3-methoxy-17-hydroxy-16,17-secoestra-1,3,5(10)-triene-16-nitrile. Newly synthesized compounds showed a complete loss of estrogenic activity.
摘要
从3-甲氧基-17-羟基-16,17-开环雌甾-1,3,5(10)-三烯-16-腈开始，合成了五种新的开环雌酮衍生物。新合成的化合物显示出完全丧失雌激素活性。
Zotero 插件