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双胞胎对中重度抑郁症与焦虑症的共病情况。

Comorbidity of major depression and anxiety disorders in twin pairs.

作者信息

Torgersen S

机构信息

Department of Psychology, University of Oslo.

出版信息

Am J Psychiatry. 1990 Sep;147(9):1199-202. doi: 10.1176/ajp.147.9.1199.

DOI:10.1176/ajp.147.9.1199
PMID:2386253
Abstract

The relationship among major depression only, major depression with anxiety disorders, and anxiety disorders only was investigated in a twin sample (N = 177 pairs). The results suggest that there is an etiological relationship between mixed major depression-anxiety disorders and major depression only but no relationship between these two conditions and anxiety disorders only. When anxiety disorders with panic attacks were analyzed, the relationship between mixed cases and major depression only and the lack of a relationship between mixed cases, major depression only, and anxiety disorders only became even clearer. Furthermore, mixed cases seemed to be more strongly influence by genetic factors than was major depression only.

摘要

在一个双胞胎样本(N = 177对)中,研究了仅患有重度抑郁症、伴有焦虑症的重度抑郁症和仅患有焦虑症之间的关系。结果表明,混合性重度抑郁-焦虑症与仅患有重度抑郁症之间存在病因学关系,但这两种情况与仅患有焦虑症之间没有关系。当分析伴有惊恐发作的焦虑症时,混合病例与仅患有重度抑郁症之间的关系以及混合病例、仅患有重度抑郁症与仅患有焦虑症之间缺乏关系变得更加明显。此外,混合病例似乎比仅患有重度抑郁症更容易受到遗传因素的强烈影响。

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