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1例经新辅助甲磺酸伊马替尼治疗后可根治性切除的巨大直肠胃肠道间质瘤

[A case of a giant rectal gastrointestinal stromal tumor radically resectable after treatment with neoadjuvant imatinib mesylate].

作者信息

Sassa Motoki, Kobayashi Yusuke, Sugeno Hidekazu, Iwadate Manabu, Suzuki Satoshi, Endo Yoshiyuki, Nakamura Izumi, Ohki Shinji, Takenoshita Seiichi

机构信息

Dept. of Organ Regulatory Surgery, Fukushima Medical University.

出版信息

Gan To Kagaku Ryoho. 2013 Jul;40(7):937-41.

PMID:23863741
Abstract

A 64-year-old male patient was diagnosed with rectal gastrointestinal stromal tumor(GIST)by prostate biopsy, because of high PSA. We considered that a radical operation was impossible because the tumor occupied the pelvis, and we suspected prostate invasion. After neoadjuvant chemotherapy(imatinib mesylate 400 mg/day), the tumor size was reduced(90×85 mm→60×50mm), and we could thus perform radical resection. The patient is currently receiving adjuvant chemotherapy (imatinib mesylate 400 mg/day), without recurrence.

摘要

一名64岁男性患者因前列腺特异性抗原(PSA)水平升高,经前列腺活检被诊断为直肠胃肠道间质瘤(GIST)。由于肿瘤占据盆腔且怀疑侵犯前列腺,我们认为无法进行根治性手术。新辅助化疗(甲磺酸伊马替尼400毫克/天)后,肿瘤大小缩小(90×85毫米→60×50毫米),因此我们得以进行根治性切除。该患者目前正在接受辅助化疗(甲磺酸伊马替尼400毫克/天),未出现复发。

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1
[A case of a giant rectal gastrointestinal stromal tumor radically resectable after treatment with neoadjuvant imatinib mesylate].1例经新辅助甲磺酸伊马替尼治疗后可根治性切除的巨大直肠胃肠道间质瘤
Gan To Kagaku Ryoho. 2013 Jul;40(7):937-41.
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引用本文的文献

1
Diagnosis and treatment of gastrointestinal stromal tumor extending to prostate: A case report and literature review.延伸至前列腺的胃肠道间质瘤的诊断与治疗:一例报告及文献复习
Medicine (Baltimore). 2016 Nov;95(46):e5439. doi: 10.1097/MD.0000000000005439.
2
Effective Downsizing of a Gastroesophageal GIST Using Neoadjuvant Imatinib Mesylate: a Case Report.使用新辅助甲磺酸伊马替尼有效缩小胃食管胃肠道间质瘤:一例报告
J Gastrointest Cancer. 2017 Jun;48(2):198-200. doi: 10.1007/s12029-016-9816-6.