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[二尖瓣心脏缺陷矫正阶段心房和心室肌细胞超微结构重组的差异]

[Differences in the ultrastructural reorganization of the myocytes of the atria and ventricles in the stages of the correction of mitral heart defects].

作者信息

Shchukin V S, Maksimov V F, Korostyshevskaia I M, Valyka E N

出版信息

Arkh Patol. 1990;52(4):25-30.

PMID:2386436
Abstract

Ultrastructure and stereomorphometry of the myocardium biopsies from 12 patients are studied at various periods of the correction of mitral vitium cordis under the conditions of total body hypothermia. It is shown that compensatory changes enhance the morphological differences between the left atrium cardiomyocytes in stenosis of the mitral aperture and those in left ventricle in deficiency of mitral valve. By the end of operation the ventricle cardiomyocytes are damaged at a higher degree showing the pronounced myofibrillary contracture. The atrium myocytes having a labile protein-synthetic apparatus are more resistant to the damaging effect of operation. Morphofunctional specialization of different heart compartments should be taken into consideration in diagnostic practice.

摘要

在全身低温条件下,对12例患者二尖瓣心畸形矫正不同阶段的心肌活检组织进行了超微结构和体视形态测量研究。结果表明,代偿性变化加剧了二尖瓣口狭窄时左心房心肌细胞与二尖瓣缺失时左心室心肌细胞之间的形态学差异。手术结束时,心室心肌细胞受损程度更高,表现出明显的肌原纤维挛缩。具有不稳定蛋白质合成装置的心房肌细胞对手术损伤作用更具抵抗力。在诊断实践中应考虑不同心脏腔室的形态功能特化。

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