Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.
J Econ Entomol. 2013 Jun;106(3):1423-9. doi: 10.1603/ec12494.
Diamondback moth, Plutella xylostella (L.) is a serious insect pest of vegetables worldwide, and has evolved resistance to various kinds of insecticides. Studies were conducted to determine the baseline toxicity of metaflumizone and the possibility of cross-resistance between metaflumizone and indoxacarb, two sodium channel blocking insecticides (SCBIs), in field populations of P. xylostella from China. The variation in susceptibility to metaflumizone among 29 field populations of P. xylostella collected from 14 geographical locations in China was less than five-fold, with 50% lethal concentrations (LC50(s)) varying from 1.34 to 6.55 mg/liter. Limited variations in LC50(s) (less than five-fold, ranging from 1.76 to 8.16 mg/liter) were also observed in the four laboratory-selected strains with high levels of resistance to abamectin, spinosad, fipronil, or Bt toxin Cry1Ac. The toxicity of metaflumizone and indoxacarb was compared among 23 out of the 29 field populations. When compared with the susceptible Roth strain, the JN-09B population showed the highest level of resistance to indoxacarb (110-fold), but two-fold tolerance to metaflumizone. The other 22 populations (with 5- to 58-fold of resistance to indoxacarb) had 1- to three-fold tolerance to metaflumizone. Metaflumizone could provide an effective alternative insecticide for diamondback moth management. Although the field populations of P. xylostella tested with various levels of resistance to indoxacarb did not have cross-resistance to metaflumizone, metaflumizone should be rotated with other chemicals of different modes of action instead of indoxacarb.
小菜蛾，Plutella xylostella（L.）是一种全球性的严重蔬菜害虫，已经对各种杀虫剂产生了抗药性。本研究旨在确定甲氟虫酰胺和茚虫威这两种钠离子通道阻断杀虫剂（SCBIs）在来自中国的小菜蛾田间种群中的基础毒性以及可能存在的交互抗性。在中国 14 个地理位置采集的 29 个小菜蛾田间种群对甲氟虫酰胺的敏感性变化不到五倍，50%致死浓度（LC50(s)）在 1.34 至 6.55 毫克/升之间。在对阿维菌素、多杀菌素、氟虫腈或 Bt 毒素 Cry1Ac 具有高水平抗性的四个实验室选择的品系中，LC50(s)（1.76 至 8.16 毫克/升之间变化不到五倍）也存在有限的变化。在 29 个田间种群中，对 23 个种群进行了甲氟虫酰胺和茚虫威的毒性比较。与敏感的 Roth 品系相比，JN-09B 种群对茚虫威表现出最高的抗性（110 倍），但对甲氟虫酰胺具有两倍的耐受性。其他 22 个种群（对茚虫威的抗性为 5 至 58 倍）对甲氟虫酰胺具有 1 至 3 倍的耐受性。甲氟虫酰胺可为小菜蛾的防治提供一种有效的替代杀虫剂。尽管测试的具有不同水平茚虫威抗性的小菜蛾田间种群对甲氟虫酰胺没有交互抗性，但甲氟虫酰胺应与其他作用方式不同的化学品轮换使用，而不是与茚虫威轮换使用。
