Aziz Saima, Soomro Nargis
Department Obstetrics & Gynaecology, Dow University of Health Sciences & Civil Hospital Karachi.
J Pak Med Assoc. 2012 Nov;62(11):1204-8.
To determine the frequency of twin births and their foetomaternal complications in women of low socioeconomic profile.
The cross-sectional study was conducted from January 2009 to December 2010 at the Obstetrics and Gynaecolgy Unit I, Civil Hospital, Karachi. Patients with twin pregnancy giving birth beyond 24 weeks, were selected by non-probability purposive sampling. Data on patient characteristics, gestation, antepartum and peripartum complications, chorionicity, mode of delivery and perinatal outcome was recorded and analysed through SPSS 16.
Out of 6077 deliveries during the study period, 119 twin births gave a frequency of 19.58/1000 births. Patients' mean age was 27.51+/-4.2 years, mean parity 2.4+/-2.2 and mean gestational age was 34.76+/-3.4 weeks. Unbooked and referred patients were 96 (80.67%). Final paired outcome was alive twin pairs in 74 (62.18%) cases, stillbirth in 7 (5.88%), neonatal deaths in 10 (8.40%). Perinatal mortality rate was 277/1000 twin births. Most frequent foetal complications were low birth weight (n=84; 70.58%), pre-term births (n=70; 58.82%) and intrauterine growth restriction (n=59; 49.57%). The second twin was at significantly higher risk (p< 0.05). Monochorionic twins had significantly high rates of stillbirths than dichorionic (p = 0.023). Most frequent maternal complications comprised pre-term labour (n=56; 47.05%), severe anaemia (n=22; 18.48%), hypertensive disorders (n=19; 15.96%) and postpartum haemorrhage (n=10; 8.40%).
Twin pregnancies in women of low socioeconomic profile result in very high rates of low birthweight, pre-term births, intrauterine growth restriction, anaemia, hypertensive disorders and postpartum haemorrhage. Monochorionic pregnancies result in high rates of stillbirths and second twin is more likely to be compromised.
确定社会经济地位较低的女性双胞胎分娩的频率及其母婴并发症。
2009年1月至2010年12月在卡拉奇市立医院妇产科一组进行了横断面研究。通过非概率立意抽样选择孕周超过24周的双胎妊娠患者。记录患者特征、孕周、产前和产时并发症、绒毛膜性、分娩方式和围产期结局等数据,并通过SPSS 16进行分析。
在研究期间的6077例分娩中,119例双胞胎分娩,频率为19.58/1000例分娩。患者平均年龄为27.51±4.2岁,平均产次为2.4±2.2,平均孕周为34.76±3.4周。未登记和转诊患者有96例(80.67%)。最终配对结局为74例(62.18%)存活双胞胎,7例(5.88%)死产,10例(8.40%)新生儿死亡。围产儿死亡率为277/1000例双胞胎分娩。最常见的胎儿并发症为低出生体重(n=84;70.58%)、早产(n=70;58.82%)和宫内生长受限(n=59;49.57%)。第二个胎儿风险显著更高(p<0.05)。单绒毛膜双胞胎的死产率显著高于双绒毛膜双胞胎(p = 0.023)。最常见的母亲并发症包括早产(n=56;47.05%)、重度贫血(n=22;18.48%)、高血压疾病(n=19;15.96%)和产后出血(n=10;8.40%)。
社会经济地位较低的女性双胎妊娠导致低出生体重、早产、宫内生长受限、贫血、高血压疾病和产后出血的发生率非常高。单绒毛膜妊娠导致死产率较高,第二个胎儿更易受到影响。