Goldust Mohamad, Sokouti Mohsen, Montazeri Vahid, Fakhrjoo Ashraf, Samankan Shabnam
Department of Thorax Surgery, Tabriz University of Medical Sciences, Iran.
J Pak Med Assoc. 2012 Nov;62(11):1265-8.
To evaluate the epidemiology and prognostic factors of thyroid cancer among children and adolescents in Tabriz, Iran.
The retrospective descriptive-analytical study, assessing the tumour and characteristics of 356 patients with thyroid carcinoma aged 5-25, was conducted at the Department of Surgery, Imam Khomeini Hospital, Tabriz University of Medical Sciences from April 1995 to April 2010. All malignant neoplasms of the thyroid gland registered during the study period were studied, and their demographic and medical data was evaluated and, compared to identify the epidemiology and prognosis factors related to survival. SPSS 16 was used for statistical analysis.
Of the total, there were 100 (28%) male and 256 (72%) female subjects, with their mean age being 12.6+/-8.4 years. In terms of the disease, there was no statistically significant difference between the two genders (p=0.65). The five-year survival rate was 345 (97%) in patients aged 5-25 years. Gender was not a statistically significant marker (p=0.82).
The study indicated an increase in cases of thyroid cancer incidence. It also underlined the need for standardisation of diagnostic, classification and registration criteria which shall be a fundamental requirement for future studies of thyroid carcinoma in young people.
评估伊朗大不里士儿童及青少年甲状腺癌的流行病学特征及预后因素。
1995年4月至2010年4月，在大不里士医科大学伊玛目霍梅尼医院外科开展了一项回顾性描述性分析研究，评估356例年龄在5至25岁的甲状腺癌患者的肿瘤情况及特征。对研究期间登记的所有甲状腺恶性肿瘤进行研究，评估其人口统计学和医学数据，并进行比较，以确定与生存相关的流行病学和预后因素。采用SPSS 16进行统计分析。
总共有100名（28%）男性和256名（72%）女性受试者，平均年龄为12.6±8.4岁。就疾病而言，两性之间无统计学显著差异（p=0.65）。5至25岁患者的五年生存率为345例（97%）。性别不是统计学上的显著指标（p=0.82）。
该研究表明甲状腺癌发病率有所上升。它还强调了诊断、分类和登记标准标准化的必要性，这将是未来青少年甲状腺癌研究的一项基本要求。
