• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
[Advances in diagnosis and treatment of brain metastases from the primary lung cancer].[原发性肺癌脑转移的诊断与治疗进展]
Zhongguo Fei Ai Za Zhi. 2013 Jul;16(7):382-6. doi: 10.3779/j.issn.1009-3419.2013.07.10.
2
Surgery versus radiosurgery for patients with a solitary brain metastasis from non-small cell lung cancer.非小细胞肺癌单发脑转移患者的手术与放射外科治疗对比
Cochrane Database Syst Rev. 2006 Jan 25;2006(1):CD004840. doi: 10.1002/14651858.CD004840.pub2.
3
Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases.全脑放疗用于治疗新诊断的多发脑转移瘤。
Cochrane Database Syst Rev. 2012 Apr 18;2012(4):CD003869. doi: 10.1002/14651858.CD003869.pub3.
4
Patients with single brain metastasis from non-small cell lung cancer equally benefit from stereotactic radiosurgery and surgery: a systematic review.非小细胞肺癌单发脑转移患者从立体定向放射外科手术和手术中获益相当：一项系统评价
Med Sci Monit. 2015 Jan 12;21:144-52. doi: 10.12659/MSM.892405.
5
123I-MIBG scintigraphy and 18F-FDG-PET imaging for diagnosing neuroblastoma.用于诊断神经母细胞瘤的123I-间碘苄胍闪烁扫描术和18F-氟代脱氧葡萄糖正电子发射断层显像
Cochrane Database Syst Rev. 2015 Sep 29;2015(9):CD009263. doi: 10.1002/14651858.CD009263.pub2.
6
Combined treatment for non-small cell lung cancer and breast cancer patients with brain metastases with whole brain radiotherapy and temozolomide: a systematic review and meta-analysis.脑转移非小细胞肺癌和乳腺癌患者行全脑放疗联合替莫唑胺治疗的系统评价和荟萃分析。
J Neurooncol. 2017 Nov;135(2):217-227. doi: 10.1007/s11060-017-2572-z. Epub 2017 Jul 19.
7
Clinical Management of Multiple Melanoma Brain Metastases: A Systematic Review.多灶性黑色素瘤脑转移的临床处理：系统评价。
JAMA Oncol. 2015 Aug;1(5):668-76. doi: 10.1001/jamaoncol.2015.1206.
8
Systematic Review of Brain Metastases in Patients With Non-Small-Cell Lung Cancer in the United States, European Union, and Japan.美国、欧盟和日本非小细胞肺癌患者脑转移的系统评价。
Clin Lung Cancer. 2017 Nov;18(6):607-614. doi: 10.1016/j.cllc.2017.04.011. Epub 2017 Apr 26.
9
Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases.全脑放疗用于治疗新诊断的多发性脑转移瘤。
Cochrane Database Syst Rev. 2018 Jan 25;1(1):CD003869. doi: 10.1002/14651858.CD003869.pub4.
10
Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases.单纯全脑放射治疗（WBRT）与全脑放射治疗联合放射外科手术治疗脑转移瘤的比较。
Cochrane Database Syst Rev. 2017 Sep 25;9(9):CD006121. doi: 10.1002/14651858.CD006121.pub4.

引用本文的文献

1
[Th17 cells and IL-17 are increased in patients with brain metastases from the primary lung cancer].[原发性肺癌脑转移患者体内的辅助性T细胞17及白细胞介素-17水平升高]
Zhongguo Fei Ai Za Zhi. 2013 Sep;16(9):476-81. doi: 10.3779/j.issn.1009-3419.2013.09.07.

本文引用的文献

1
Recursive partitioning analysis classification and graded prognostic assessment for non-small cell lung cancer patients with brain metastasis: a retrospective cohort study.递归分区分析分类和非小细胞肺癌脑转移患者的分级预后评估：一项回顾性队列研究。
Chin J Cancer Res. 2011 Sep;23(3):177-82. doi: 10.1007/s11670-011-0177-1.
2
Coregistered whole body magnetic resonance imaging-positron emission tomography (MRI-PET) versus PET-computed tomography plus brain MRI in staging resectable lung cancer: comparisons of clinical effectiveness in a randomized trial.全身磁共振成像-正电子发射断层扫描（MRI-PET）与 PET-计算机断层扫描加脑 MRI 在可切除肺癌分期中的比较：一项随机试验中的临床效果比较。
Cancer. 2013 May 15;119(10):1784-91. doi: 10.1002/cncr.28000. Epub 2013 Feb 19.
3
Pemetrexed and cisplatin combination with concurrent whole brain radiotherapy in patients with brain metastases of lung adenocarcinoma: a single-arm phase II clinical trial.培美曲塞和顺铂联合全脑放疗治疗肺腺癌脑转移患者：一项单臂 II 期临床试验。
J Neurooncol. 2013 May;112(3):461-6. doi: 10.1007/s11060-013-1079-5. Epub 2013 Feb 19.
4
Phase II trial of erlotinib plus concurrent whole-brain radiation therapy for patients with brain metastases from non-small-cell lung cancer.厄洛替尼联合全脑放疗治疗非小细胞肺癌脑转移患者的 II 期临床试验。
J Clin Oncol. 2013 Mar 1;31(7):895-902. doi: 10.1200/JCO.2011.40.1174. Epub 2013 Jan 22.
5
Continuous pemetrexed treatment for brain metastasis in non-small cell lung cancer--a report of two cases.培美曲塞持续治疗非小细胞肺癌脑转移——两例报告
Lung Cancer. 2013 Apr;80(1):111-3. doi: 10.1016/j.lungcan.2012.12.010. Epub 2012 Dec 29.
6
EGF receptor tyrosine kinase inhibitors in the treatment of brain metastases from non-small-cell lung cancer.表皮生长因子受体酪氨酸激酶抑制剂治疗非小细胞肺癌脑转移。
Expert Rev Anticancer Ther. 2012 Nov;12(11):1429-35. doi: 10.1586/era.12.121.
7
Hypofractionated stereotactic radiotherapy with or without whole-brain radiotherapy for patients with newly diagnosed brain metastases from non-small cell lung cancer.立体定向放射治疗与或不与全脑放疗治疗非小细胞肺癌脑转移患者的新诊断病例。
J Neurosurg. 2012 Dec;117 Suppl:49-56. doi: 10.3171/2012.7.GKS121071.
8
Brain metastases as the first symptom of lung cancer: a clinical study from an Asian medical center.脑转移作为肺癌的首发症状：来自亚洲医学中心的一项临床研究。
J Cancer Res Clin Oncol. 2013 Mar;139(3):403-8. doi: 10.1007/s00432-012-1344-6. Epub 2012 Nov 4.
9
Efficacy and limitations of salvage gamma knife radiosurgery for brain metastases of small-cell lung cancer after whole-brain radiotherapy.全脑放疗后挽救性伽玛刀放射外科治疗小细胞肺癌脑转移的疗效和局限性。
Acta Neurochir (Wien). 2013 Jan;155(1):107-13; discussion 113-4. doi: 10.1007/s00701-012-1520-0. Epub 2012 Oct 13.
10
Miliary brain metastasis presenting with calcification in a patient with lung cancer: a case report.肺癌患者出现钙化的粟粒性脑转移：一例报告
J Med Case Rep. 2012 Sep 4;6:279. doi: 10.1186/1752-1947-6-279.

[原发性肺癌脑转移的诊断与治疗进展]

[Advances in diagnosis and treatment of brain metastases from the primary lung cancer].

作者信息

Liu Yi, Chen Jun

机构信息

Department of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China.

出版信息

Zhongguo Fei Ai Za Zhi. 2013 Jul;16(7):382-6. doi: 10.3779/j.issn.1009-3419.2013.07.10.

DOI:10.3779/j.issn.1009-3419.2013.07.10
PMID:23866671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6000654/
Abstract

Lung cancer with brain metastasis was 23% to 65%, and is the most common type in brain metastasis tumors with the poor prognosis. At present, diagnosis and treatment of brain metastases from lung carcinoma and its molecular mechanism have become one hot spot of amount researches. Here, we made a systematic review of the progress of the clinical features, diagnosis and treatment of brain metastases from lung and its molecular mechanism.

摘要

肺癌脑转移率为23%至65%，是脑转移瘤中最常见的类型，预后较差。目前，肺癌脑转移的诊断与治疗及其分子机制已成为众多研究的热点之一。在此，我们对肺癌脑转移的临床特征、诊断与治疗进展及其分子机制进行了系统综述。