Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, PR China.
Eur J Obstet Gynecol Reprod Biol. 2013 Sep;170(1):225-8. doi: 10.1016/j.ejogrb.2013.06.015. Epub 2013 Jul 15.
To explore the association between epithelial ovarian cancer (EOC) and common benign gynecological disorders.
The medical records of 226 patients with EOC treated at Peking Union Medical College Hospital between March 2011 and March 2012 were reviewed. Histological evaluations had been performed to determine the presence of coexisting pelvic endometriosis (n=17), uterine leiomyoma (n=66), adenomyosis (n=22), or endometrial polyps (n=17).
Coexistence of endometriosis occurred in 35.3% and 36.4% of cases of the clear cell and endometrioid subtypes of EOC histology, respectively. Endometriosis was more likely associated with clear cell or endometrioid ovarian carcinoma, but less likely with high grade serous cancer. No differences were observed in the concurrence of uterine myoma, adenomyosis or endometrial polyps among the different subtypes of EOC.
In contrast to other common benign gynecological disorders, endometriosis showed close relationships with the clear cell and endometrioid subtypes of EOC specifically.
探讨上皮性卵巢癌（EOC）与常见妇科良性疾病的关系。
回顾分析 2011 年 3 月至 2012 年 3 月在北京协和医院接受治疗的 226 例上皮性卵巢癌患者的病历。通过组织学评估确定是否存在并存的盆腔子宫内膜异位症（n=17）、子宫肌瘤（n=66）、子宫腺肌病（n=22）或子宫内膜息肉（n=17）。
子宫内膜异位症分别存在于 35.3%和 36.4%的透明细胞和子宫内膜样卵巢癌组织学亚型中。子宫内膜异位症与透明细胞或子宫内膜样卵巢癌的关系更为密切，但与高级别浆液性癌的关系则不密切。在不同的 EOC 组织学亚型中，子宫肌瘤、子宫腺肌病或子宫内膜息肉的并存率没有差异。
与其他常见妇科良性疾病相比，子宫内膜异位症与透明细胞和子宫内膜样卵巢癌有密切关系。
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